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TWiV 939: From lizards to Lassa with Tom Monath

25 September 2022 by Vincent Racaniello

Tom Monath joins TWiV to discuss his wide-ranging career that includes medicine, field work and vaccine development while working for the US government, the US military, and multiple biotechnology companies.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Guest: Tom Monath

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: Acambis, COVID-19, dengue vaccine, ebola virus, Lassa virus, NewLink Genetics, vaccine, vaccine platform, viral, virology, virus, viruses, yellow fever virus

TWiV 633: Singapore viral

30 June 2020 by Vincent Racaniello

From DukeNUS Medical School, Vincent speaks with Ashley, Sheemei, Eng Eong and Dahai about their careers and their research on flaviviruses and sensing of viral RNA.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: dengue virus, DukeNUS, flavivirus, interferon, RIG-I, RNA sensor, viral, virology, virus, viruses, yellow fever virus

Fatal yellow fever in a transplant recipient

23 May 2019 by Vincent Racaniello

FlavivirusInfection with yellow fever virus caused the death of a patient 25 years after receiving a kidney transplant, illustrating the difficulties associated with some medical vaccine exemptions.

The patient had received a kidney transplant at the age of 58 in February 1993. Nearly 25 years later he was admitted to hospital with two days of fever, nausea, and vomiting. A sonogram revealed an enlarged right lobe of the liver, but tests for hepatitis A, B, C and HIV-1 were negative. He progressed to hepatic insufficiency and acute liver failure and died 6 days after admission to hospital.

[Read more…] about Fatal yellow fever in a transplant recipient

Filed Under: Basic virology, Information Tagged With: hepatic failure, immunosuppression, medical vaccine exemption, organ transplant, viral, virology, virus, viruses, yellow fever vaccine, yellow fever virus

TWiV 535: Miles to go before I leak

17 February 2019 by Vincent Racaniello

The TWiV team discuss the use of quantum dots to study uncoating of influenza virus in real time, and induction of endothelial dysfunction by flavivirus NS1 proteins in a tissue-specific manner.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: dengue virus, endocytosis, flavivirus, glycocalyx, influenza virus, NS1, nuclear import, pathogenesis, quantum dot, ribonucleoprotein, vascular leak, viral, viremia, virology, virus, viruses, West Nile virus, yellow fever virus, zika virus

TWiV 471: Songs of innocence and experience

10 December 2017 by Vincent Racaniello

The TWiVerinos discuss restriction of dengue virus vaccine by Sanofi, and data which suggest that Dengvaxia causes enhanced disease in previously uninfected recipients.

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Download TWiV 471 (66 MB .mp3, 108 min)
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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: ADE, antibody dependent enhancement, dengue virus, Dengvaxia, flavivirus, TV003, vaccine enhanced disease, viral, virology, virus, yellow fever virus

TWiV 375: Zika and you will find

7 February 2016 by Vincent Racaniello

TWiVOn episode #375 of the science show This Week in Virology, the TWiVziks present everything you want to know about Zika virus, including association of infection with microcephaly and Guillain-Barré syndrome, transmission, epidemiology, and much more.

You can find TWiV #375 at microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: Aedes, antiviral, Brazil, Dengue, flavivirus, GBS, Guillain-Barré syndrome, microcephaly, mosquito, vaccine, viral, virology, virus, viruses, West Nile virus, yellow fever virus, Zika, zika virus

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

With David Tuller and
Gertrud U. Rey

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