xmrv

Ila Singh finds no XMRV in patients with chronic fatigue syndrome

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Since the first association of the retrovirus XMRV with chronic fatigue syndrome in 2009 in the US, subsequent studies have failed to detect evidence of infection in patients from the US, Europe, and China. These studies were potentially compromised by a number of factors, such as differences in patient characterization, geographic locations, clinical samples used, …

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TWiV 129: We’ve got mail

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Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Rich Condit Vincent, Alan, Dickson and Rich answer listener questions about XMRV, yellow fever vaccine, virus-like particles, West Nile virus, amyotrophic lateral sclerosis and human endogenous retroviruses, multiplicity of infection, and how to make a poxvirus. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV129.mp3″] Click the arrow above to play, or right-click to download …

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TWiV 123: Contaminated prostates, absolute truth, and bleached worms

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #123 of the podcast This Week in Virology, Vincent, Alan, and Rich talk about XMRV integration sites in prostate tumor DNA, the decline effect and scientific method, and the first virus of Caenorhabditis nematodes. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV123.mp3″] Click the arrow above to play, or right-click to download TWiV #123 …

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Authenticity of XMRV integration sites

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Integration of retroviral DNA into the cellular genome is essential for the production of new infectious particles. A strong argument that the novel human retrovirus XMRV is not a laboratory contaminant is the finding that viral DNA is integrated in chromosomal DNA of prostate tumors. Nucleotide sequence analyses of 14 integration sites in prostate tumor DNAs …

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