Wuhan

Furin cleavage site in the SARS-CoV-2 coronavirus glycoprotein

46 Comments / Basic virology, Information / By

The spike glycoprotein of the newly emerged SARS-CoV-2 contains a potential cleavage site for furin proteases. This observation has implications for the zoonotic origin of the virus and its epidemic spread in China. The membrane of coronaviruses harbors a trimeric transmembrane spike (S) glycoprotein (pictured) which is essential for entry of virus particles into the …

Furin cleavage site in the SARS-CoV-2 coronavirus glycoprotein Read More »

TWiV 586: Coronavirus update: wash your hands

6 Comments / This Week in Virology / By

In this week’s coverage of the coronavirus epidemic, the TWiV team discusses the fatality rate, China’s initial reaction to the outbreak, conspiracy theories, how long the virus remains infectious on surfaces, and evidence for virus in the intestinal tract. Click arrow to play Download TWiV 586 (72 MB .mp3, 119 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! …

TWiV 586: Coronavirus update: wash your hands Read More »

TWiV 585: The coronavirus epidemic

This Week in Virology / By

The TWiVerers continue their coverage of the new coronavirus outbreak in China, as the number of cases increase dramatically and the virus begins person-to-person transmission in other countries. Click arrow to play Download TWiV 585 (71 MB .mp3, 118 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

TWiV 584: Year of the coronavirus

2 Comments / This Week in Virology / By

Coronavirus expert Ralph Baric joins TWiV to explain the virology and epidemiology of the recent zoonotic outbreak spreading across China and overseas. Click arrow to play Download TWiV 584 (64 MB .mp3, 106 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv

A lesson from SARS-CoV for 2019-nCoV

10 Comments / Basic virology, Information / By

As with all previous outbreaks of new virus infections, we are being warned of impending doom concerning the new coronavirus, 2019-nCoV that is now spreading globally. China€™s National Health Commission Vice Minister Li Bin recently warned that ‘there is the possibility of viral mutation€™. Perhaps Mr. Li is unaware that viral genomes sustain mutations during …

A lesson from SARS-CoV for 2019-nCoV Read More »

Scroll to Top