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About viruses and viral disease

virus-like particle

TWiV 477: Raiders of the lost Arc

21 January 2018 by Vincent Racaniello

The TWiVodrome explains how a gag-like protein from a retrotransposon forms virus-like particles that carry mRNA within vesicles across the synapse.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: Arc, darc, drosophila, exovesicles, gag, jumping genes, neuron, retrotransposon, retrovirus, synapse, transposable element, viral, virology, virus, virus-like particle, viruses

TWiV 459: Polio turns over a new leaf

17 September 2017 by Vincent Racaniello

The TWiV team reviews the first FDA approved gene therapy, accidental exposure to poliovirus type 2 in a manufacturing plant, and production of a candidate poliovirus vaccine in plants.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: accidental exposure, acute lymphoblastic leukemia, Agrobacterium, CAR, chimeric antigen receptor, empty capsid, gene therapy, inactivated polio vaccine, IPV, Kymriah, lentivirus vector, Nicotiana, plant, poliovirus, tobacco, vaccine, viral, virology, virus, virus-like particle, vlp

TWiV 372: Latent viral tendencies

17 January 2016 by Vincent Racaniello

TWiVOn episode #372 of the science show This Week in Virology, the TWiV-osphere introduces influenza D virus, virus-like particles encoded in the wasp genome which protect its eggs from caterpillar immunity, and a cytomegalovirus protein which counters a host restriction protein that prevents establishment of latency.

You can find TWiV #372 at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: caterpillar, cytomegalovirus, Daxx, histone acetylation, histone methylation, influenza C, influenza D, intrinsic defenses, latency, lysine demethylase, nudivirus, UL138, viral, virology, virus, virus-like particle, viruses, wasp

TWiV #170: From variolous effluvia to VLPs

12 February 2012 by Vincent Racaniello

cow-pock

On This Week in Virology #170, hosts Alan, Rich, and Dickson discuss Edward Jenner’s paper on cowpox vaccine, then move 200 years later to modern vaccines against norovirus, influenza H5N1, and more.

You can find TWiV #170 at www.microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: cowpox, edward jenner, H5N1, hexavalent pediatric, influenza, norovirus, smallpox, vaccine, viral, virology, virus, virus-like particle, vlp

TWiV 129: We’ve got mail

17 April 2011 by Vincent Racaniello

rich unwindsHosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Rich Condit

Vincent, Alan, Dickson and Rich answer listener questions about XMRV, yellow fever vaccine, virus-like particles, West Nile virus, amyotrophic lateral sclerosis and human endogenous retroviruses, multiplicity of infection, and how to make a poxvirus.

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Click the arrow above to play, or right-click to download TWiV #129 (67 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

  • HTLV-2 sequences in patients with CFIDS
  • Self-assembling virus (YouTube)
  • BookFinder
  • Ilya’s photo (jpg)
  • Discussion about CROI at ViroBlogy
  • Land cover and West Nile virus disease (Am Journ Trop Med Hyg)
  • Construction of recombinant poxviruses (Methods Mol Biol)
  • Geographic Information System
  • TWiV on Facebook
  • Letters read on TWiV 129

Weekly Science Picks

Rich – Polyxeni Potter and EID covers
Dickson – American Museum of Natural History
Alan –
Moon Trees (EurekAlert! article)
Vincent – Infection Landscapes

Listener Picks of the Week

Didier  – The Vaccines (MySpace)
/Sven-Urban –
The Science of Discworld by Terry Pratchett
Garren – Omega Tau podcast

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: als, CFS, endogenous retrovirus, ERV, moi, multiplicity of infection, podcast, poxvirus, smallpox, viral, virology, virus, virus-like particle, West Nile virus, xmrv, yellow fever

TWiV 47: Vertical vaccine farm

30 August 2009 by Vincent Racaniello

twiv-200Hosts: Vincent Racaniello and Dick Despommier

On episode #47 of the podcast “This Week in Virology”, Vincent and Dick discuss influenza virus-like particle vaccines produced in insect and plant cells, rapid sharing of influenza research, and answer listener questions about cytomegalovirus, viral evolution and symbiosis and much more.

[powerpress url=”http://traffic.libsyn.com/twiv/TWiV047.mp3″]

Click the arrow above to play, or right-click to download TWiV #47 (51 MB .mp3, 71 minutes)

Subscribe to TWiV in iTunes, by the RSS feed, or by email

Links for this episode:
A Farm on Every Floor
Influenza virus-like particles in insect and plant cells
PLoS Currents: Influenza
Transmission of 2009 H1N1 influenza virus to turkeys [Thanks Debbie!]
Baxter produces Vero cell H1N1 vaccine [Thanks Peter!]
Boundaries of Darwinism podcast [Thanks David!]
Phages in human intestine: papers one, two, three [Thanks Terry!]
Post-exposure varicella vaccine [Thanks Patricia!]
Open science movement here, here, here, and here [Thanks Jim!]
Graduate programs in virology [Thanks Greggory and Blake!]
Post-exposure Marburg and Ebola vaccines [Thanks John!]
Vaccinia infection in the laboratory [Thanks Russ!]
Animations of bacteriophage T4 life cycle [Thanks Jim!]

Weekly Science Picks
Vincent Bionumbers
Dick Ocean: An Illustrated Atlas by Sylvia A. Earle, Linda K. Glover

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv or leave voicemail at Skype: twivpodcast

Filed Under: This Week in Virology Tagged With: bacteriophage, cytomegalovirus, Ebola, H1N1, influenza, marburg, open science, pandemic, plant, swine flu, vaccine, varicella virus, vertical farm, viral, virology, virus, virus-like particle

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

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