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About viruses and viral disease

transcriptome

Planaria and mollusks yield the biggest RNA virus genomes

30 August 2018 by Vincent Racaniello

planarianThe development of high throughput nucleic acid sequencing tools has rapidly increased the pace of virus discovery in the past 20 years. Yet in that time, while the largest DNA genomes have increased by nearly ten times, the largest known RNA viral genome has only increase in size by a tenth. This situation has now changed with the discovery of new RNA viruses of planarians and mollusks.

[Read more…] about Planaria and mollusks yield the biggest RNA virus genomes

Filed Under: Basic virology, Information Tagged With: Aplysia, genome, genome size, mollusk, nidovirus, planaria, RNA, transcriptome, viral, virology, virus, viruses

Mosquito blood feeding is not a free lunch

15 March 2018 by Vincent Racaniello

Wyeomyia smithiiImagine that we could change all the mosquitoes in the world so that they would no longer take a blood meal, and then consider the impact on transmission of viruses and parasites. Before you say impossible, you should know that Nature has already done it – not all mosquitoes take blood meals.

[Read more…] about Mosquito blood feeding is not a free lunch

Filed Under: Basic virology, Information Tagged With: biting mosquito, blood meal, mosquito, non-biting mosquito, pitcher plant mosquito, transcriptome, viral, virology, virus, viruses, Wyeomyia smithii

TWiV 390: Building a better mosquito trap

22 May 2016 by Vincent Racaniello

TWiVProject Premonition, a Microsoft Research project that uses drones to capture mosquitoes and analyze them for pathogens, preprint servers, and three mouse models for Zika virus induced birth defects are the topics of episode #390 of the science show This Week in Virology.

You can find TWiV #390 at microbe.tv/twiv, or listen below.

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Filed Under: This Week in Virology Tagged With: arbovirus, bioRxive, drone, genome sequencing, microcephaly, mosquito, mosquito trap, mouse model, preprint server, Project Premonition, RNAseq, transcriptome, viral, virology, virus, viruses, zika virus

TWiV 187: The mummy

10 June 2012 by Vincent Racaniello

On episode #187 of the science show This Week in Virology, Vincent and Rich discuss recovery of a hepatitis B viral genome from a 16th century Korean mummy, and personal omics profiling of an individual over a 14 month period.

You can find TWiV #187 at www.microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: ancient dna, autoantibody, genome, HBV, hepatitis b virus, ipop, Korea, metabolome, mike snyder, mummy, personal omics profiling, proteome, respiratory syncytial virus, rhinovirus, transcriptome, viral, virology, virus

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by Vincent Racaniello

Earth’s virology Professor
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