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STAT2

A Mouse Model System for Zika Virus Infection

14 June 2018 by Gertrud U. Rey

IFN signaling
Type I IFN receptor binding and signal transduction.

By Gertrud U. Rey

Zika virus (ZIKV) infection causes microcephaly in newborns and is causally associated with Guillian-Barré syndrome in adults. To date, there are no drugs available to prevent or treat ZIKV infection. ZIKV vaccine research is challenging because adult immunocompetent mice are resistant to ZIKV infection and disease.

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Filed Under: Basic virology, Gertrud Rey, Information Tagged With: IFN, immune evasion, interferon, microcephaly, mouse model, pathogenesis, STAT2, viral, virology, virus, viruses, zika virus

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