An explanation for the low quality antibodies produced during serious SARS-CoV-2 infection

Although we are less than a year into the SARS-CoV-2 pandemic, it appears that the antibodies induced by infection are often of poor quality, and B cell memory seems limited. An explanation for this outcome might be a consequence of the loss of germinal centers in COVID-19 patients. Examination of lymph nodes and spleen of …

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