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TWiV 269: Herpesvirus stops a nuclear attack

26 January 2014 by Vincent Racaniello

On episode #269 of the science show This Week in Virology, the complete TWiV team reviews evidence for sensing of herpesviral DNA in the nucleus by the cell protein IFI16.

You can find TWiV #269 at www.microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: acetylation, degradation, DNA, IFI16, innate immunity, interferon, nuclear localization signal, nucleus, proteasome, sensor, ubiquitin, viral, virology, virus

TWiM 30: Unraveling melioidosis and insulin resistance

4 April 2012 by Vincent Racaniello

On episode #30 of the science show This Week in Microbiology, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor.

You can find TWiM #30 at microbeworld.org/twim.

Filed Under: This Week in Microbiology Tagged With: burkholderia, gut, immune, innate, insulin, melioidosis, mice, microbiome, protein, pseudomallei, resistance, sensor, synthesis, toxin

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by Vincent Racaniello

Earth’s virology Professor
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