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About viruses and viral disease

restriction factor

TWiV 511: Accessory found guilty in DC

16 September 2018 by Vincent Racaniello

Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: AIDS, dendritic cell vaccine, dNTP, HIV-1, hiv-2, human immunodeficiency virus, latent reservoir, myeloid cell, Ned Landau, restriction factor, reverse transcription, SAMHD1, siv, viral, virology, virus, viruses, Vpx

TWiV 465: Theodora the explorer

29 October 2017 by Vincent Racaniello

Theodora Hatziioannou joins the TWiV team to discuss a macaque model for AIDS, and how a cell protein that blocks HIV-1 infection interacts with double-stranded RNA.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: AIDS, animal model, APOBEC3H, CRNA, deamination, dsRNA, HIV-1, pigtail macaque, restriction factor, viral, virology, virus, viruses, X-ray structure

TWiV 409: A Nef is enough

2 October 2016 by Vincent Racaniello

Jeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered and found to promote infection by excluding the host protein SERINC from virus particles.

You can find TWiV #409 at microbe.tv/twiv, or listen below.

[powerpress url=”http://traffic.libsyn.com/twiv/TWiV409.mp3″]

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Filed Under: This Week in Virology Tagged With: AIDS, endocytosis, HIV, Nef, restriction factor, SERINC, siv, viral, virion, virology, virus, viruses

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

With David Tuller and
Gertrud U. Rey

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