by Gertrud U. Rey Almost sixty years have passed since the initial formalin-inactivated respiratory syncytial virus (RSV) vaccine caused enhanced disease in children when they were subsequently infected with the virus. Since then, RSV has continued to be a substantial public health threat to infants, young children, and older people. Although progress in developing a …
TWiV provides an update on immunity to Omicron, results of a randomized controlled trial of face masks, and a study of correlates of protection against respiratory syncytial virus infection in the upper and lower respiratory tract of nonhuman primates. Click arrow to playDownload TWiV 841 (63 MB .mp3, 105 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Show notes at microbe.tv/twiv
During viral replication, defective genomes may arise that lack essential sequences. These so-called defective genomes cannot replicate unless they are in the same cell as a helper virus. Defective genomes play a role in modulating pathogenesis of respiratory syncytial virus in humans. Copy-back defective viral genomes (cbDVGs) of RSV arise when the viral RNA polymerase …
Defective genomes modulate respiratory syncytial virus pathogenesis Read More »
Kizzmekia Corbett joins TWiV to review her career and her work on respiratory syncytial virus, influenza virus, and coronaviruses and coronavirus vaccines, including her role in development and testing of a spike-encoding mRNA vaccine, and then we review the Nobel Prize for discovery of hepatitis C virus. Click arrow to playDownload TWiV 670 (76 MB .mp3, …
TWiV 670: Coronavirus vaccine preparedness with Kizzmekia Corbett Read More »
From Georgia State University, Vincent speaks with Chris, Andrew, Priya, and Richard about their careers and their work on Ebolaviruses, rotavirus, and antiviral drug development. Click arrow to playDownload TWiV 636 (68 MB .mp3, 113 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
By Gertrud U. Rey Respiratory syncytial virus (RSV) is a leading cause of respiratory illness, including bronchiolitis and pneumonia, in the young, elderly, and immunocompromised. RSV poses a substantial public health threat due to its association with severe morbidity and mortality in infants and premature babies.
