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TWiV 540: Wascally wiruses

24 March 2019 by Vincent Racaniello

The TWiVstars reveal the diversity of herpes simplex virus type 2 in a neonatal population, and parallel adaptation of rabbits in three countries to myxoma virus.

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Filed Under: This Week in Virology Tagged With: adaptation, comparative genomics, genome sequence, herpes simplex virus, herpes simplex virus type 2, human herpesvirus 2, minor variants, myxoma virus, neonatal, neonate, neurovirulence, parallel evolution, poxvirus, rabbit, viral, viral spread, virology, virus, viruses

Rabbits and viruses: An iconic example of natural selection

21 March 2019 by Vincent Racaniello

Rabbits around the waterholeWhen viruses are introduced into a new population, selection pressures can lead to evolution of both pathogen and host. The pathogen must adapt to a new host, while the latter can become resistant to infection, leading to an arms race. An archetypal example of such host-pathogen evolution is illustrated by the attempt to control rabbit populations in Australia by the release of a pathogenic virus. Recent work illuminates the changes that occurred as the rabbits became resistant to infection.

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Filed Under: Basic virology, Information Tagged With: australia, evolution, myxoma virus, natural selection, rabbit, viral, virology, virus, viruses

TWiV 457: The Red Queen meets the White Rabbit

3 September 2017 by Vincent Racaniello

Brianne returns to the TWiV Gang to discuss the distribution of proteins on the influenza viral genome, and the evolution of myxoma virus that was released in Australia to control the rabbit population.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: frank fenner, immunosuppression, influenza virus, myxoma virus, NP, nucleocapsid, nucleoprotein, rabbit, ribonucleoprotein, RNP, viral, virology, virulence evolution, virus, viruses

TWiV 284: By the pricking of my thumbs, something wicked this way comes

11 May 2014 by Vincent Racaniello

On episode #284 of the science show This Week in Virology, the TWiV team discusses how skin scarification promotes a nonspecific immune response, and whether remaining stocks of smallpox virus should be destroyed.

You can find TWiV #284 at www.microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: bifurcated needle, intradermal, rabbit, scarification, smallpox, vaccinia virus, viral, virology, virulence, virus, WHO

TWiV 67: Wasting deer and the Hulk rabbit

24 January 2010 by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, and Marc Pelletier

Vincent, Alan, and Marc talk about chronic wasting disease of deer caused by prions, blocking the semen-derived enhancer of HIV infection with surfen, and making green transgenic rabbits using a lentiviral vector.

This episode is sponsored by Data Robotics Inc. Use the promotion code VINCENT to receive $50 off a Drobo or $100 off a Drobo S.

[powerpress url=”http://traffic.libsyn.com/twiv/TWiV067.mp3″]

Click the arrow above to play, or right-click to download TWiV #67 (64 MB .mp3, 88 minutes)

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Links for this episode:

  • Chronic wasting disease in West Virginia
  • Chronic wasting disease alliance and CDC webpage
  • Semen-derived inhibitor of viral infection (SEVI)
  • Surfen inhibits the action of SEVI
  • Making green transgenic rabbits using simian immunodeficiency virus vector
  • Science comedy (thanks Lucky Fractal!)

Weekly Science Picks
Marc Association of Science-Technology Centers Passport Program
Alan Zooniverse
Vincent Grand Rounds at the Mailman School of Public Health

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: AIDS, chronic wasting disease, deer, GFP, green fluorescent protein, HIV, podcast, prion, rabbit, semen, sevi, surfen, transgenic, transmissible spongiform encephalopathy, TWiV, viral, virology, virus

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

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