prostate cancer

TWiV 320: Retroviruses and cranberries

On episode #320 of the science show This Week in Virology, Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries. You can find TWiV #320 at www.microbe.tv/twiv.

TWiV 164: Six steps forward, four steps back

Hosts: Vincent Racaniello, Rich Condit, and Alan Dove Vincent, Alan, and Rich review ten compelling virology stories of 2011. Please help us by taking our listener survey. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV164.mp3″] Click the arrow above to play, or right-click to download TWiV 164 (60 MB .mp3, 99 minutes). Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, …

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TWiV 123: Contaminated prostates, absolute truth, and bleached worms

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #123 of the podcast This Week in Virology, Vincent, Alan, and Rich talk about XMRV integration sites in prostate tumor DNA, the decline effect and scientific method, and the first virus of Caenorhabditis nematodes. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV123.mp3″] Click the arrow above to play, or right-click to download TWiV #123 …

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Authenticity of XMRV integration sites

Integration of retroviral DNA into the cellular genome is essential for the production of new infectious particles. A strong argument that the novel human retrovirus XMRV is not a laboratory contaminant is the finding that viral DNA is integrated in chromosomal DNA of prostate tumors. Nucleotide sequence analyses of 14 integration sites in prostate tumor DNAs …

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Retroviral integration and the XMRV provirus

A strong argument that the novel human retrovirus XMRV is not a laboratory contaminant is the finding that viral DNA is integrated in chromosomal DNA of prostate tumors. Why does this result constitute such strong proof of viral infection? Establishment of an integrated copy of the viral genome – the provirus – is a critical …

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