with Amy Rosenfeld
Enterovirus D68 (EV-D68) was first isolated from children with respiratory disease in 1962. No outbreaks of infection were detected until the late summer and early fall of 2014, and then in 2016 and 2018. During these epidemics of respiratory disease, some children developed polio-like paralysis. We have recently published a paper showing that isolates of EV-D68 from 1962 through 2014 are capable of infecting cells of the nervous system, disproving the hypothesis that neurotropism of the virus is a recently acquired phenotype.