PML

TWiV 150: Contaminated

Hosts: Vincent Racaniello, Rich Condit, and Dickson Despommier Vincent, Dickson, and Rich meant to do an all-email episode, but first they review results of the Blood XMRV Scientific Research Working Group, and partial retraction of the paper associating XMRV with chronic fatigue syndrome. With this episode TWiV is three years old. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV150.mp3″] Click the arrow above …

TWiV 150: Contaminated Read More »

Polyomavirus JC, multiple sclerosis, Tysabri, and an anti-malaria drug

Biogen has announced that an anti-malaria compound may be useful for treating a brain infection, progressive multifocal leukoencephalopathy (PML), that is an adverse effect of the company’s multiple sclerosis/Crohn’s disease drug Tysabri. How does JC virus fit into this story? Tysabri is the trade name for Natalizumab, a monoclonal antibody against the cellular protein alpha-4 integrin. …

Polyomavirus JC, multiple sclerosis, Tysabri, and an anti-malaria drug Read More »

Scroll to Top