pandemic

Oseltamivir resistance decreases influenza aerosol transmission

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The isolates of influenza virus obtained in the current global outbreak have proven to be resistant to the adamantane antivirals, but susceptible to oseltamivir (Tamiflu) and zanamivir (Relenza). Consequently the two neuraminidase inhibitors will likely be used extensively to control the outbreak until a vaccine is available. Extended use of the antiviral drugs will undoubtedly …

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Swine influenza A/Mexico/2009 (H1N1) update

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Here is an update on the global swine flu situation as of 29 April 2009. Not surprisingly, laboratory confirmed case counts continue to rise globally. There are 91 cases in the US in 10 states (Arizona, California, Indiana, Kansas, Massachusetts, Michigan, Nevada, New York, Ohio, Texas). There has been a laboratory confirmed fatal case in …

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Swine influenza, seasonality, and the northern hemisphere

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I have received several questions about my assertion that the northern hemisphere is safe, at least until the fall, from an epidemic of A/California/09/2009 influenza virus. Here are two representative questions: If I recall correctly, Spanish flu hit hardest during the summer and fall. As for the swine flu, is it impossible (and why?) to …

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