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myxoma virus

TWiV 540: Wascally wiruses

24 March 2019 by Vincent Racaniello

The TWiVstars reveal the diversity of herpes simplex virus type 2 in a neonatal population, and parallel adaptation of rabbits in three countries to myxoma virus.

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Filed Under: This Week in Virology Tagged With: adaptation, comparative genomics, genome sequence, herpes simplex virus, herpes simplex virus type 2, human herpesvirus 2, minor variants, myxoma virus, neonatal, neonate, neurovirulence, parallel evolution, poxvirus, rabbit, viral, viral spread, virology, virus, viruses

Rabbits and viruses: An iconic example of natural selection

21 March 2019 by Vincent Racaniello

Rabbits around the waterholeWhen viruses are introduced into a new population, selection pressures can lead to evolution of both pathogen and host. The pathogen must adapt to a new host, while the latter can become resistant to infection, leading to an arms race. An archetypal example of such host-pathogen evolution is illustrated by the attempt to control rabbit populations in Australia by the release of a pathogenic virus. Recent work illuminates the changes that occurred as the rabbits became resistant to infection.

[Read more…] about Rabbits and viruses: An iconic example of natural selection

Filed Under: Basic virology, Information Tagged With: australia, evolution, myxoma virus, natural selection, rabbit, viral, virology, virus, viruses

TWiV 457: The Red Queen meets the White Rabbit

3 September 2017 by Vincent Racaniello

Brianne returns to the TWiV Gang to discuss the distribution of proteins on the influenza viral genome, and the evolution of myxoma virus that was released in Australia to control the rabbit population.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: frank fenner, immunosuppression, influenza virus, myxoma virus, NP, nucleocapsid, nucleoprotein, rabbit, ribonucleoprotein, RNP, viral, virology, virulence evolution, virus, viruses

TWiV 124: Viruses that make you better

13 March 2011 by Vincent Racaniello

Rabbits Myxomatosis Trial WardangIsland 1938Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Grant McFadden

On episode #124 of the podcast This Week in Virology, Vincent, Dickson, Alan, Rich, and Grant discuss a tanapoxvirus protein that inhibits tumor necrosis factor, purging tumors with myxoma virus, and destruction of the last known stocks of smallpox virus.

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Click the arrow above to play, or right-click to download TWiV #124 (74 MB .mp3, 103 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

  • Interaction of tumor necrosis factor with tanapox virus protein
  • Viron Therapeutics Inc
  • Oncolytic viral purging with myxoma virus
  • Why not destroy remaining smallpox stocks? (editorial)
  • US should agree to destroy smallpox stocks (CIDRAP)
  • TWiV on Facebook
  • Letters read on TWiV 124

Weekly Science Picks

Grant – A Short History of Nearly Everything by Bill Bryson
Dickson – An Inquiry into the Causes and Effects of the Variolae Vaccinae by Edward Jenner
Rich –
Selinah (Topsy Foundation) thanks Meghan!
Alan – Draft report (pdf) on WHO’s H1N1 response and NY Times summary
Vincent – 10 stunning science visualizations

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: bioterrorism, cancer therapy, myxoma virus, oncolysis, oncolytic, poxvirus, smallpox, tanapox virus, tumor, viral, virology, virus

TWiV 84: Gators go viral

30 May 2010 by Vincent Racaniello

Hosts: Vincent Racaniello, Rich Condit, Dave Bloom, and Grant McFadden

On episode #84 of the podcast This Week in Virology, Vincent and Rich spoke with Dave Bloom and Grant McFadden about their work on herpesviruses and poxviruses in this episode recorded before an audience at the University of Florida, Gainesville – home of the Gators.

This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo.

Win a free Drobo S! Contest rules here.

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Click the arrow above to play, or right-click to download TWiV #84 (71 MB .mp3, 99 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

  • Epigenetic modulation of herpes simplex virus gene expression (thanks, Matthew!)
  • The Red Queen and Tierra virtual environment: article one, two, three (thanks, Jesper!)
  • Hand-held HIV detector (thanks, Jim!)
  • Anti-angiogenic cancer therapy combined with oncolytic virotherapy (thanks, Bill!)
  • TWiV at UF Gainesville (jpg)
  • Letters read on TWiV 84

Weekly Science Picks

Rich – Charles F. Littlewood photographs
Vincent
– Not so humble pie (thanks, Sophie!)
Grant – The Strangest Man by Graham Farmelo
David – Is Parkinson’s Disease a prion disorder?

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: david bloom, gainesville, gators, grant mcfadden, herpes simplex virus, herpesvirus, myxoma virus, oncolytic virotherapy, poxvirus, viral, virology, virus

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by Vincent Racaniello

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