by Gertrud U. Rey Norovirus is the most common food-borne virus and the leading cause of gastroenteritis globally. Despite an urgent need, there are currently no licensed vaccines to prevent norovirus-induced illness. Nevertheless, recent developments in this field have led to remarkable and promising new advances. A phase 1b clinical trial has revealed that a …
Rhesus macaques that are vaccinated against SARS-CoV-2 are protected from severe disease and probably transmit very little virus when infected with SARS-CoV-2 one year later.
by Gertrud U. Rey There are currently 315 therapeutic drugs and 210 vaccine candidates in development to treat or prevent SARS-CoV-2 infection. Many of these vaccines are designed to be administered by injection into the muscle. Intramuscular injection of a vaccine antigen typically induces a systemic (serum) immune response that involves the action of IgM and IgG …
Sociomedical scientist Robert Fullilove joins TWiV to discuss disparities in minority health; FDA announces an EUA on Yale’s SalivaDirect, protection of the upper and respiratory tract of mice after intranasal inoculation with an adenovirus-vectored SARS-CoV-2 spike gene, and listener questions. Click arrow to playDownload TWiV 655 (88 MB .mp3, 147 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show …
Although the use of the live, attenuated (Sabin) poliovirus vaccines has been instrumental in nearly eradicating the virus from the planet, the rare reversion to virulence of these strains has lead to the World Health Organization to recommend their replacement with inactivated poliovirus vaccine (IPV). Unfortunately IPV is also not without shortcomings, including high cost, failure …
Whole plant cells producing viral capsid protein as a poliovirus vaccine candidate Read More »
On episode #356 of the science show This Week in Virology, Stephanie joins the super professors to discuss the gut virome of children with serious malnutrition, caterpillar genes acquired from parasitic wasps, and the effect of adding chemokines to a simian immunodeficiency virus DNA vaccine. You can find TWiV #356 at www.microbe.tv/twiv.
