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About viruses and viral disease

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A Live-Attenuated Herpes Simplex Virus Vaccine Candidate

24 May 2018 by Gertrud U. Rey

herpesvirusBy Gertrud U. Rey

There is currently no vaccine to prevent infection with herpes simplex virus type 1 or type 2 (HSV-1 or HSV-2). Infection with either of these viruses results in life-long viral latency. Sporadic reactivation and viral shedding may lead to painful oral and genital disease and an increased risk of HIV transmission.

[Read more…] about A Live-Attenuated Herpes Simplex Virus Vaccine Candidate

Filed Under: Basic virology, Gertrud Rey, Information Tagged With: guinea pig, herpes simplex virus, herpesvirus, latency, mouse, reactivation, vaccine, viral, virology, virus, viruses

TWiV 452: Kiss that frog

30 July 2017 by Vincent Racaniello

Lynda Coughlan joins the weekly virtual bus companions for a discussion of a host defense peptide from frogs that destroys influenza virus, and mouse models for acute and chronic hepacivirus infection.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: amphibian, antibody, CD4, CD8, checkpoint blockade, defensins, frog, hemagglutinin, hepacivirus, hepatitis, hepatitis C virus, host defense peptide, influenza virus, magainin, mouse, Norway rat hepacivirus, PD-1, viral, virology, virus, viruses

TWiV 236: Flu gets the VIP treatment

9 June 2013 by Vincent Racaniello

On epside #236 of the science show This Week in Virology, Vincent, Alan and Kathy review novel approaches to preventing influenza virus infection.

You can find TWiV #236 at www.microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: aav, adeno-associated virus, broadly neutralizing antibody, codon pair bias, ferret, HA, hemagglutinin, influenza, mouse, NA, neuraminidase, vaccine, vector, vectored immunoprophylaxis, viral, virology, virus

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

With David Tuller and
Gertrud U. Rey

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