mIR-122

TWiV 389: Alphabet hepatitis with Stan Lemon

Vincent speaks with Stan Lemon about his career in virology, from early work on Epstein Barr virus, through making essential discoveries about hepatitis A virus, hepatitis C virus, and rhinoviruses, on episode #389 of the science show This Week in Virology. You can find TWiV #389 at microbe.tv/twiv, or listen below. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV389.mp3″] Click arrow to …

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Treating hepatitis C by blocking a cellular microRNA

Miravirsen is a drug that binds to and blocks the function of a cellular microRNA called miR-122 that is required for the replication of hepatitis C virus (HCV). Treatment of chimpanzees chronically infected with HCV with this drug leads to suppression of viral replication. The results of a phase 2b human clinical trial in HCV …

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TWiV 97: California virology

Hosts: Vincent Racaniello, Peter Sarnow, and Bert Semler On episode #97 of the podcast This Week in Virology, Vincent visited Peter Sarnow and Bert Semler during a trip to California, and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV097.mp3″] Click …

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