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TWiM 29: Death and an iron-loaded spike

21 March 2012 by Vincent Racaniello

On episode #29 of the podcast This Week in Microbiology, Vincent and Stanley review how a phage pierces the cell membrane with an iron-loaded spike, and two programmed cell death systems in E. coli.

You can find TWiM #29 at microbeworld.org/twim.

Filed Under: This Week in Microbiology Tagged With: addiction system, apoptosis, bacteriophage spike, e.coli, mazEF, microbe, microbiology

TWiM #18: Escherichia coli K-12, an emerging pathogen?

19 October 2011 by Vincent Racaniello

This Week in MicrobiologyHosts: Vincent Racaniello, Michael Schmidt, Stanley Maloy and Elio Schaechter.

On episode #18 of the podcast This Week in Microbiology, Vincent, Michael, Elio, and Stanley explain how to make the human intestinal commensal and benign laboratory bacterium Escherichia coli K-12 into an invasive organism, and the unearthing of century-old spores in New York City.

[powerpress url=”http://traffic.libsyn.com/twimshow/TWiM018.mp3″]

Click the arrow above to play, or right-click to download TWiM #18 (54 MB, .mp3, 74 minutes).

Subscribe to TWiM (free) on iTunes, Zune Marketplace, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

  • Conversion of E. coli K-12 to an invasive form (mBio)
  • Pedigree of E. coli K-12 (pdf)
  • The facade of E. coli K-12 (Small Things Considered)
  • Unearthing of century old bacteria in NYC (ABC News)
  • Bacteria in 30,000 year old salt crystals (Geology)
  • Old bacteria in ice
  • Old, small, cold… (Small Things Considered)
  • IP6 mediated autoprocessing of bacterial toxins (PloS Path)
  • Letters read on TWiM #18

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Filed Under: This Week in Microbiology Tagged With: bacterium, benign, coli, commensal, ecoli, escherichia, human, intestinal, invasive, k-12, laboratory, microbe, microbiology, new york, organism, spores

TWiM 17: Debugging endosymbiosis

6 October 2011 by Vincent Racaniello

planococcus citriHosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

Vincent, Michael and Elio focus on endosymbiosis: the rapid spread of Ricekttsia in whitefiles, and a metabolic patchwork in nested symbionts of mealybugs.

[powerpress url=”http://traffic.libsyn.com/twimshow/TWiM017.mp3″]

Click the arrow above to play, or right-click to download TWiM #17 (51 MB, .mp3, 70 minutes).

Subscribe to TWiM (free) on iTunes, Zune Marketplace, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

  • Nested symbiosis in mealybugs (Curr Bio)
  • A bug in a bug in a bug (STC)
  • Rapid spread of an endosymbiont in whitefly (Science)
  • Instant evolution in whiteflies (UANews)
  • Letters read on TWiM #17

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Filed Under: This Week in Microbiology Tagged With: endosymbiosis, mealybug, metabolic, microbe, microbiology, nested, patchwork, rapid, Ricekttsia, spread, symbionts, whiteflies

TWiM 16: ICAAC Live

22 September 2011 by Vincent Racaniello

This Week in Microbiology

Hosts: Vincent Racaniello, Michael Schmidt, Arturo Casadevall, Stuart Levy, and David Livermore.

Vincent, Michael, Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease, at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

[powerpress url=”http://traffic.libsyn.com/twimshow/TWiM016.mp3″]

Click the arrow above to play, or right-click to download TWiM 16 (65 MB, .mp3, 90 minutes).

Subscribe to TWiM (free) on iTunes, Zune Marketplace, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

  • Need for new antibacterials (J Antimicr Chem)
  • Consumer antibacterial soaps (Clin Inf Dis)
  • Endothermy and fungal growth (mBio)
  • Bat white-nose syndrome (Microbe)
  • Chytrid fungus in amphibians

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Filed Under: This Week in Microbiology Tagged With: antibacterial, antibiotic, carbapenem, fungi, microbe, microbiology, ndm-1, resistance, triclosan

TWiV and TWiM live at ICAAC in Chicago

15 September 2011 by Vincent Racaniello

twiv icaac 2011The Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) is the annual infectious diseases meeting of the American Society for Microbiology. This year the meeting will take place in Chicago, Illinois, and both This Week and Virology and This Week in Microbiology will be broadcast live from the meeting.  TWiV will air on Saturday, September 17, at 2:00 PM CDT, and TWiM will air on Monday, September 19, at 11:15 AM CDT, at McCormick Place in room W-470B.

Meeting attendees are welcome to attend and watch live TWiV and TWiM and submit comments and questions during the show. The podcasts will be broadcast live and archived online at UStream.tv, at MicrobeWorld, and virology blog. During the live broadcasts a chat room will be available for listeners to submit questions.

Here are the participants for ICAAC TWiV and TWiM:

Saturday, 17 September, 2:00 pm CDT – This Week in Virology with Vincent Racaniello and friends

  • Trine Tsouderos, Health/Medical Writer, Chicago Tribune
  • Mark Pallansch, Ph.D., Chief of the Enterovirus Section in the National Center for Infectious Diseases at the U.S. Centers for Disease Control

Monday, 19 September, 11:15 am CDT – This Week in Microbiology with Vincent Racaniello and friends

  • Stuart B. Levy, MD, Professor, Tufts Univ. School of Medicine/CSO, Paratek Pharmaceuticals, Tufts Univ. Sch. of Med., Boston, MA.
  • Arturo Casadevall, MD, Ph.D., Professor and Chair, Albert Einstein Coll. of Med. of Yeshiva Univ., Bronx, NY.
  • David Livermore, Ph.D., HPA Centre for Infections, London, United Kingdom

Filed Under: Events, This Week in Microbiology, This Week in Virology Tagged With: icaac, microbe, podcast, viral, virology, virus

This Week in Microbiology (TWiM) #12: Photothermal nanoblades and genome engineering

29 July 2011 by Vincent Racaniello

intracellular modelHosts: Vincent Racaniello, Michael Schmidt, Margaret McFall-Ngai, and Elio Schaechter

On episode #12 of the podcast This Week in Microbiology, Vincent, Margaret, Michael and Elio review the use of photothermal nanoblades to dissect the Burkholderia intracellular life cycle, and manipulation of chromosomes in vivo for genome-wide codon replacement in E. coli.

[powerpress url=”http://traffic.libsyn.com/twimshow/TWiM012.mp3″]

Click the arrow above to play, or right click to download TWiM #12 (52 MB, .mp3, 75 minutes).

Subscribe to TWiM (free) on iTunes, Zune Marketplace, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

  • Using a photothermal nanoblade to study intracellular life cycle (PNAS)
  • Reynolds number
  • Theriot lab movie collection
  • Manipulation of chromosomes in vivo (Science)
  • Stop codons
  • Church’s personal genomes project
  • Letters read on TWiM #12

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Filed Under: This Week in Microbiology Tagged With: bacteria, burkholderia, e.coli, engineering, genome, intracellular, microbe, microbiology, nanoblades, Photothermal

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by Vincent Racaniello

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