memory B cells

A Viral Risk Factor for Lupus

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by Gertrud U. Rey Epstein-Barr virus (EBV) is a common human herpesvirus that typically spreads through saliva and is known for causing infectious mononucleosis (i.e., “mono”). There is an established causal link between infection with EBV and the development of multiple sclerosis. Emerging evidence now suggests that EBV may also play a significant role in …

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An explanation for the low quality antibodies produced during serious SARS-CoV-2 infection

Basic virology / By

Although we are less than a year into the SARS-CoV-2 pandemic, it appears that the antibodies induced by infection are often of poor quality, and B cell memory seems limited. An explanation for this outcome might be a consequence of the loss of germinal centers in COVID-19 patients. Examination of lymph nodes and spleen of …

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