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TWiV 454: FGCU, Zika

13 August 2017 by Vincent Racaniello

Sharon Isern and Scott Michael return to TWiV for a Zika virus update, including their work on viral evolution and spread, and whether pre-existing immunity to dengue virus enhances pathogenesis.

 

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: ADE, aedes aegyptii, antibody dependent enhancement, dengue virus, epidemiology, evolution, macaque, microcephaly, mosquito, mucosal transmission, pathogenesis, phylogenetic tree, viral, virology, virus, viruses, wolbachia, zika virus

TWiV 429: Zika Experimental Science Team

19 February 2017 by Vincent Racaniello

Vincent meets with members of team ZEST at the University of Wisconsin Madison to discuss their macaque model for Zika virus pathogenesis.

You can find TWiV #429 at microbe.tv/twiv, or listen/watch right here.

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Filed Under: This Week in Virology Tagged With: macaque, microcephaly, mosquito, pathogenesis, rhesus, sexual transmission, viral, virology, virus, viruses, zika virus

TWiV 122: More fun than a monkey full of viruses

27 February 2011 by Vincent Racaniello

japanese macaquesHosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Welkin Johnson

On episode #122 of the podcast This Week in Virology, the complete TWiV crew teams up with Welkin Johnson to explore the other AIDS epidemic, infection of monkeys with simian immunodeficiency virus, and its restriction by the cellular protein TRIM5.

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Click the arrow above to play, or right-click to download TWiV #122 (77 MB .mp3, 147 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

  • Edwin Kilbourne, MD, 1920-2011
  • Evolution of TRIM5-CypA in Old World monkeys (PLoS Pathogens)
  • Balancing selection and evolution of Old World TRIM5 (PNAS)
  • TRIM5 and cross-species transmission of a primate retrovirus (PLoS Biology)
  • Infectious retrovirus in pet vaccines (J Virology)
  • TWiV on Facebook
  • Letters read on TWiV 122

Weekly Science Picks

Welkin – Supramap
Dickson – Science issue on visualizing data
Rich – Doonesbury weighs in on vaccines and autism

Alan – US National Vaccine Plan
Vincent – US Supreme Court decision on vaccine litigation (NY Times)

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: AIDS, endogenous retrovirus, ERV, macaque, old world monkey, retroviral restriction, simian immunodeficiency virus, siv, trim5, viral, virology, virus, welkin johnson

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by Vincent Racaniello

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