virology blog
About viruses and viral disease
Patrick Moore returns to TWiV to discuss the discovery from the Chang-Moore laboratory of circular RNAs in cells infected with herpesviruses.
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Show notes at microbe.tv/twiv
The diversity of cellular RNA structure and function has progressed from the early days of molecular biology, when we thought only about mRNA, tRNA and ribosomal RNAs. Then RNA splicing was discovered along with the many small nuclear RNAs that mediate that process. Next came small interfering RNAs and microRNAs and long noncoding RNAs, master regulators of cell processes. The latest addition to the RNA toolbox are circular RNAs (circRNA), first found in viroids, then cells, and now encoded in the genomes of two herpesviruses.
In the first of two shows recorded at the University of North Carolina in Chapel Hill, Vincent meets up with faculty members to talk about how they got into science, their research on DNA viruses, and what they would be doing if they were not scientists.
You can find TWiV #407 part one at microbe.tv/twiv. Or watch the video above, or listen below.
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Download TWiV 407a (43 MB .mp3, 71 min)
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On episode #359 of the science show This Week in Virology, Vincent speaks with Blossom about her laboratory’s research on Kaposi’s sarcoma-associated herpesvirus, including how it transforms cells, the switch between lytic and latent replication, and its interaction with the innate immune system of the host.
You can find TWiV #359 at www.microbe.tv/twiv.
On episode #228 of the science show This Week in Virology, Vincent visits the University of California at Berkeley and speaks with Britt Glaunsinger and Eva Harris about their work on Kaposi’s sarcoma associated herpesvirus and dengue virus.
You can find TWiV #228 at www.microbe.tv/twiv.
We recorded This Week in Virology #202 at the University of Nebraska in Lincoln, Nebraska on 5 October 2012, as part of the 12th Annual Symposium in Virology. Terence Dermody, Shou-Wei Ding, Grant McFadden and I spoke about our research, and then we recorded TWiV with University of Nebraska virologists James Van Etten, T. Jack Morris, and Charles Wood.
I was impressed by the fine virology being done at the Nebraska Center for Virology, as well as the collegiality of the virology community in Nebraska, Iowa, South Dakota, and Kansas – Symposium attendees were from all of those states! I met many young virologists at the poster session and I was touched by how many of them wanted to say hello and thank us for doing TWiV.
Many thanks to all the virologists who came to the Symposium and stayed to watch TWiV. Special thanks to Charles Wood, the Director of the Nebraska Center for Virology, who participated in TWiV #202 along with T. Jack Morris and James Van Etten.
Here are some behind the scenes photographs of this short but very informative visit.
