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TWiV 462: Splicing RNA with Phillip A. Sharp

10 October 2017 by Vincent Racaniello

Vincent speaks with 1993 Nobel Laureate Phillip A. Sharp about his career and his seminal discovery of RNA splicing in mammalian cells, which changed our understanding of gene structure.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: exon, intervening sequence, intron, lariat, Phillip A. Sharp, rna splicing, spliceosome, split genes, viral, virology, virus, viruses

TWiV 339: Herpes and the sashimi plot

31 May 2015 by Vincent Racaniello

On episode #339 of the science show This Week in Virology, tre TWiV amici present three snippets and a side of sashimi: how herpesvirus inhibits host cell gene expression by disrupting transcription termination.

You can find TWiV #339 at www.microbe.tv/twiv.

Filed Under: Uncategorized Tagged With: cancer, Chikungunya virus, exon, herpesvirus, host shutoff, intron, IRF7, Lassa fever, mosquitoes, splicing, transcription termination, translation, viral, virology, virus, West Nile virus

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by Vincent Racaniello

Earth’s virology Professor
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