• Skip to main content
  • Skip to primary sidebar
virology blog

virology blog

About viruses and viral disease

influenza vaccine

TWiV 887: Bonfire of the monocytes

10 April 2022 by Vincent Racaniello

TWiV explains why this season’s influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld

Click arrow to play
Download TWiV 887 (65 MB .mp3, 108 min)
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

Become a patron of TWiV!

Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: antibody dependent enhancement, coronavirus, COVID-19, Fc receptor, fucosylation, glycosylation, H3N2, inflammation, influenza vaccine, pandemic, SARS-CoV-22, viral, virology, virus, viruses

Longevity of SARS-CoV-2 memory B cells

10 September 2020 by Vincent Racaniello

Immunity conferred by influenza virus vaccine is short-lived. After immunization with inactivated influenza virus vaccine, serum antibody levels peak within a few months and then decline rapidly. This decline was recently shown to be caused by loss of bone marrow plasma cells, a major source of serum antibodies. Results of a recent study partially address the relevance of this observation to infection with SARS-CoV-2.

[Read more…] about Longevity of SARS-CoV-2 memory B cells

Filed Under: Basic virology, Information Tagged With: antibody, B cell, bone marrow plasma cell, COVID-19, influenza vaccine, memory B cell, pandemic, plasmablast, SARS-CoV-2, viral, virology, virus, viruses

TWiV 660: In case of emergency finish the trial

10 September 2020 by Vincent Racaniello

Daniel Griffin provides a clinical report on COVID-19, then we discuss decline of virus-specific bone marrow B cells within a year after influenza vaccination, the push to release SARS-CoV-2 vaccines before completion of phase 3 trials, and absence of evidence for infectious virus in aerosols.

Click arrow to play
Download TWiV 660 (95 MB .mp3, 159 min)
Subscribe (free): iTunes, Google Podcasts, RSS, email

Become a patron of TWiV!

Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: aerosol transmission, bone marrow B cells, clinical trial, coronavirus, COVID-19, diagnostic tests, influenza vaccine, pandemic, SARS-CoV-2, vaccine, viral, virology, virus, viruses

TWiV 582: This little virus went to market

12 January 2020 by Vincent Racaniello

TWiV provides updates on the new coronavirus causing respiratory disease in China, the current influenza season, and the epidemic of African swine fever, including determination of the three-dimensional structure of the virus particle.

Click arrow to play
Download TWiV 582 (71 MB .mp3, 118 min)
Subscribe (free): iTunes, Google Podcasts, RSS, email

Become a patron of TWiV!

Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: african swine fever virus, capsid, China, coronavirus, cryo-electron micrography, giant virus, Huanan Fish Market, influenza, influenza excess mortality, influenza like illness, influenza vaccine, pig, swine, three dimensional virus structure, viral, virology, virus, viruses, Wuhan pneumonia, zoonosis

Antibiotics blunt the antibody response to influenza vaccine

19 December 2019 by Vincent Racaniello

influenza vaccineThe human gut microbiome appears to play diverse roles in host physiology, metabolism, and immunity. Most conclusions about what the trillions of bacteria in our intestines actually do come from studies in mice, or correlative studies in humans. An exception is an investigation in humans which shows that antibiotic-mediated alteration of the fecal microbiome* interferes with the antibody response to influenza vaccine.

[Read more…] about Antibiotics blunt the antibody response to influenza vaccine

Filed Under: Basic virology, Information Tagged With: antibiotics, antibody response, influenza vaccine, influenza virus, microbiome, trivalent inactivated influenza vaccine, viral, virology, virus, viruses

TWiV 571: Piwi koalas

27 October 2019 by Vincent Racaniello

The League of Extraordinary Virologists celebrate the eradication of wild poliovirus type 3, and consider the effectiveness of an influenza vaccine produced in insect cells, and how small RNAs are protecting the Koala germline from retroviral invasion.

Click arrow to play
Download TWiV 571 (64 MB .mp3, 105 min)
Subscribe (free): iTunes, Google Podcasts, RSS, email

Become a patron of TWiV!

Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: baculovirus, endogenous retrovirus, Flu, Flublock, Flucelvax, germline, HA, influenza, influenza vaccine, insect cell, Koala, koala retrovirus, piRNA, transposon, viral, virology, virus, viruses

  • Go to page 1
  • Go to page 2
  • Go to Next Page »

Primary Sidebar

by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

With David Tuller and
Gertrud U. Rey

Follow

Facebook, Twitter, YouTube, Instagram
Get updates by RSS or Email

Contents

Table of Contents
ME/CFS
Inside a BSL-4
The Wall of Polio
Microbe Art
Interviews With Virologists

Earth’s Virology Course

Virology Live
Columbia U
Virologia en Español
Virology 101
Influenza 101

Podcasts

This Week in Virology
This Week in Microbiology
This Week in Parasitism
This Week in Evolution
Immune
This Week in Neuroscience
All at MicrobeTV

Useful Resources

Lecturio Online Courses
HealthMap
Polio eradication
Promed-Mail
Small Things Considered
ViralZone
Virus Particle Explorer
The Living River
Parasites Without Borders

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.