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immunocompromised

TWiEVO 79: When the immune system is away, SARS-CoV-2 will play

2 July 2022 by Vincent Racaniello

Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness.

Hosts: Nels Elde and Vincent Racaniello

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Show notes at microbe.tv/twievo

Filed Under: This Week in Evolution Tagged With: antibody evasion, chronic infection, coronavirus, COVID-19, evolution, fitness, immunocompromised, natural selection, pandemic, SARS-CoV-2

TWiV 676: Tragic gene flow from Neanderthals

29 October 2020 by Vincent Racaniello

In this episode we explain how regions of the human genome associated with severe COVID-19 are identified, the finding that one of these regions was inherited from Neanderthals, and prolonged SARS-CoV-2 reproduction in an immunocompromised patient.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: coronavirus, COVID-19, genome wide association study, GWAS, immunocompromised, immunosuppressed, pandemic, SARS-CoV-2, single nucleotide polymorphism, SNIP, viral, virology, virus

TWiV 520: This old mouse

18 November 2018 by Vincent Racaniello

The TWiVidae review universal influenza vaccines that are in clinical trials, and discovery of an atypical parvovirus that causes chronic kidney disease in middle aged, immunocompromised laboratory mice.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: chronic kidney disease, clinical trial, HA stalk vaccine, immunocompromised, immunosufficient, influenza, kidney fibrosis, parvovirus, peptide, tubulointerstitial nephropathy, universal influenza vaccine, viral, virology, virus, viruses

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

With David Tuller and
Gertrud U. Rey

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Contents

Table of Contents
ME/CFS
Inside a BSL-4
The Wall of Polio
Microbe Art
Interviews With Virologists

Earth’s Virology Course

Virology Live
Columbia U
Virologia en Español
Virology 101
Influenza 101

Podcasts

This Week in Virology
This Week in Microbiology
This Week in Parasitism
This Week in Evolution
Immune
This Week in Neuroscience
All at MicrobeTV

Useful Resources

Lecturio Online Courses
HealthMap
Polio eradication
Promed-Mail
Small Things Considered
ViralZone
Virus Particle Explorer
The Living River
Parasites Without Borders

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