immune evasion

A Mouse Model System for Zika Virus Infection

14 June 2018 by Gertrud U. Rey

IFN signaling — Type I IFN receptor binding and signal transduction.

By Gertrud U. Rey

Zika virus (ZIKV) infection causes microcephaly in newborns and is causally associated with Guillian-Barré syndrome in adults. To date, there are no drugs available to prevent or treat ZIKV infection. ZIKV vaccine research is challenging because adult immunocompetent mice are resistant to ZIKV infection and disease.

[Read more…] about A Mouse Model System for Zika Virus Infection

TWiP 32: Evasive trypanosomes and schistosomes

9 November 2011 by Vincent Racaniello

Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss immune evasion by the cruzain protease of T. cruzi, and novel tetraspanin antigens of S. japonicum.

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Links for this episode:

NF-kappaB:Â NuclearÂ Factor bindingÂ kappa enhancer inÂ BÂ cells
Immune evasion by T. cruzi cruzain (PLoS Pathogens)
Novel tetraspanins in S. japonicum (Acta Tropica)
Intravenously administered malaria vaccine (Science)
TWiP on trypanosomes (#15) and schistosomes (#26)
Monsters Inside Me
Futures in Biotech with Dr. Jack Horner, advisor for Jurassic Park
Dickson’s Pick: Labcoats in Hollywood by David Kirby
Letters read on TWiP 32

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