Back in 2013 I built a Wall of Polio in my laboratory – a large stack ofÂ six-well cell culture plates that have been used to measure the concentration of polioviruses in various samples byÂ plaque assay. It became a focal point of the lab at which many guests came to have their photographs taken. Sadly, the Wall fell twice. Now a new Wall – version 3.0 – has been completed.
The new Wall of Polio is in my office at Columbia University Medical Center, where it will not annoyÂ the Fire Inspector (the former Wall partially blocked an aisle). Furthemore, the new Wall is glued together, so it will not come apart. Its construction is documented in the photographs below. The Wall of Polio 3.0 is built with 1,464 six-well plates of HeLa cells that were used to determine the titer of poliovirus.Â We have also already had a number of visitors to Wall 3.0.
Because the Wall is impressive, it attracts attention, which can then be used to explain the plaque assay and determining virus titer. Therefore it is simply another tool that I used to teach the world about virology.
When you visit, expect that I will ask to photograph you before the Wall. Only a few have refused.