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genome packaging

TWiV 518: Hershey’s viruses

4 November 2018 by Vincent Racaniello


hershey virus

Vincent travels to Penn State College of Medicine in Hershey, PA to speak with Nick Buchkovich and Leslie Parent about their careers and their work on human cytomegalovirus and retroviruses.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: ESCRT pathway, exosome, Gag protein, genome packaging, HCMV, HIV-1, human cytomegalovirus, late domain, nuclear experience, retrovirus, rous sarcoma virus, viral, virology, virus, viruses

TWiV 380: Viruses visible in le microscope photonique

13 March 2016 by Vincent Racaniello

TWiVOn episode #380 of the science show This Week in Virology, the TWiVeroos deliver the weekly Zika Report, then talk about a cryoEM structure of a plant virus that reveals how the RNA genome is packaged in the capsid, and MIMIVIRE, a CRISPR-like defense system in giant eukaryotic viruses.

You can find TWiV at microbe.tv/twiv, or you can listen below.

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Filed Under: This Week in Virology Tagged With: amoeba, birth defects, capsid, central nervous system, congenital zika syndrome, cowpea mosaic virus, CRISPR/Cas, cryoEM, genome packaging, Guillain-Barré syndrome, intrinsic defense, meningoencephalitis, microcephaly, MIMIVIRE, mimivirus, myelitis, viral, virology, viruria, virus, viruses, zika virus

TWiV 158: Wolverines go viral

20 November 2011 by Vincent Racaniello

poliovirus + CD155Hosts: Vincent Racaniello, Rich Condit, Alice Telesnitsky, and Kathy Spindler

Vincent and Rich visit the Microbiology and Immunology Department at the University of Michigan Medical School, and speak with Alice and Kathy about their work on HIV genome dimerization, and packaging and pathogenesis of mouse adenovirus.

Model of poliovirus bound to CD155 made by Stefan Taube.

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Links for this episode:

  • Mouse adenovirus infection of macrophages (Virology)
  • Breakdown of blood-brain barrier by mouse adenovirus (J Virol)
  • Major locus for mouse adenovirus susceptibility (J Immunol)
  • Structures in HIV 5′-end that regulate genome packaging (Science)
  • Packaging of host RNAs by murine leukemia virus (J Virol)
  • What, how, when, where, and why of retroviral genome dimerization and packaging (PLoS Path)
  • Virologist replaces Steve Jobs at Apple
  • TWiV on Facebook
  • Letters read on TWiV 158

Weekly Science Picks

Alice – Banvard’s Folly by Paul S. Collins
Kathy – The world at seven billion
Rich – The Princess Bride
Vincent – Center for the history of microbiology

Listener Pick of the Week

Tim – Dead Ends to Somewhere by Richard L. Ward
Don – Ben Goldacre: Battling bad science (TED)

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: genome dimerization, genome packaging, HIV, mouse adenovirus, retrovirus, viral, virology, virus

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by Vincent Racaniello

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