virology blog
About viruses and viral disease
by Gertrud U. Rey
Some viruses have a lipid envelope surrounding their protein capsid, which they get from the host cell membrane during the budding process. The envelope acts as an anchor for viral glycoproteins, which facilitate entry of the newly budded virus into a new cell by recognizing and binding host cell receptors. Such “enveloped” viruses are distinct from “naked” viruses, which lack this envelope because they exit the cell by lysing it.
The TWiVers present mitoviruses, which infect mitochondria, and how quasi-enveloped hepatitis A virus gets naked again.
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Download TWiV 541 (54 MB .mp3, 89 min)
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Show notes at microbe.tv/twiv
The TWiV team discuss the use of quantum dots to study uncoating of influenza virus in real time, and induction of endothelial dysfunction by flavivirus NS1 proteins in a tissue-specific manner.
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Download TWiV 535 (58 MB .mp3, 96 min)
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Show notes at microbe.tv/twiv
The TWiV crew reveal a unique portal on the calcivirus capsid formed upon receptor engagement, and the regulation of interferon responses in virus-infected cells by methylation of mRNA.
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Download TWiV 534 (57 MB .mp3, 95 min)
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Show notes at microbe.tv/twiv
The TWiVerati follow up on the Ebola virus outbreak, virulence of Ebola-Makona, and reveal how a parasitoid is revealed to hyperparasitoids, and binding of influenza virus to a calcium ion channel to mediate influenza virus entry.
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Download TWiV 495 (67 MB .mp3, 111 min)
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