Several mutations that arose during the 2013-2016 outbreak of Ebola virus in West Africa were previously found to increase infectivity for human cells. However, a study in two animal models show no effect of these mutations on disease. Among the many mutations identified among the hundreds of genome sequences obtained during the 2013-2016 Ebola virus epidemic, a …
Ebola virus mutations do not affect pathogenicity Read More »
The TWiV Masters discuss serologic evidence of Ebolavirus infection in a population with no outbreaks, and the set of endogenous viral elements in the mosquito genome. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span><span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: …
TWiV 482: Don’t EVEome without antibody expressed Read More »
Ebolavirus infections are feared because of the high fatality rate observed during outbreaks, from 25-90%. But there is evidence that far less serious Ebolavirus infections may occur in the absence of outbreaks.
