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About viruses and viral disease

codon usage

Virus-proof cells?

3 May 2018 by Vincent Racaniello

I am very skeptical about the pronouncement this week that a group of scientists plan to engineer cells to resist virus infection.

The initiative is called Genome-Project-write (GP-write) and is composed of an international group of collaborators with the broader goal of designing and assembling a synthetic human genome. The first goal of this consortium, reported in Science (“Genome writing project aims to rally scientists around virus-proofing cells”), Time (“Scientists announce plan to create virus-proof cells”) and many other news sources, is to create human cells that cannot be infected with all known viruses.

Could such virus-proof cells be made, and what would they be used for?

[Read more…] about Virus-proof cells?

Filed Under: Basic virology, Commentary, Information Tagged With: codon, codon usage, mRNA, protein synthesis, recoding, synthetic biology, synthetic human genome, viral, virology, virus, virus proof cells, virus resistant cells, viruses

TWiV 362: Gotta catch ’em all

8 November 2015 by Vincent Racaniello

On episode #362 of the science show This Week in Virology, the virus virtuosos, with their usual verve, illuminate a new method to identify all the viral nucleic acids in a sample, and regulation of viral gene expression by codon usage.

You can find TWiV #362 at www.microbe.tv/twiv.

Filed Under: Basic virology, This Week in Virology Tagged With: codon usage, gene regulation, herpesvirus, lipkin, mRNA synthesis, REV, temporal gene regulation, trans-activation, viral, VirCapSeq-VERT, virology, virome, virome capture sequencing, virus

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

With David Tuller and
Gertrud U. Rey

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