The human gut microbiome appears to play diverse roles in host physiology, metabolism, and immunity. Most conclusions about what the trillions of bacteria in our intestines actually do come from studies in mice, or correlative studies in humans. An exception is an investigation in humans which shows that antibiotic-mediated alteration of the fecal microbiome* interferes with the antibody response to influenza vaccine.
On episode #11 of the podcast This Week in Microbiology,Â Vincent, Margaret, Michael and Elio review the presence of extended spectrum beta-lactamase genes in chicken meat and in humans, and a beneficial effect of Helicobacter pyloriÂ colonization on the development of allergen-induced asthma.
Click the arrow above to play, or right click to download TWiM #11 (47 MB, .mp3, 68 minutes).
Links for this episode:
- Beta-lactamase genes in Enterobacteriaceae of humans and chickens (EID)
- Is drug resistance in humans coming from chickens? (Wired)
- Pew Commission on industrial farm animal production
- H. pylori infection prevents asthma in mice (JCI)
- Consequences of disappearing human microbiota (Nat Rev Micro)
- Letters read on TWiM #11
Send your microbiology questions and comments (email or mp3 file) to firstname.lastname@example.org, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.