virology blog
About viruses and viral disease
The TWiV team discusses Medusavirus, isolated from a hot spring in Japan, and induction of neurodegeneration by recurrent herpes simplex virus 1 infection of mice.
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Download TWiV 543 (65 MB .mp3, 108 min)
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Show notes at microbe.tv/twiv
In the first episode for 2019, the TWiV team reviews the amazing virology stories of the past year.
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Download TWiV 528 (77 MB .mp3, 128 min)
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The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer’s Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.
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Download TWiV 519 (58 MB .mp3, 96 min)
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Alois Alzheimer was the first to propose that an infection might play a role in the disease named after him. Herpes simplex virus type 1 (HSV-1) has been most frequently linked to Alzheimer’s Disease (AD), and a clinical trial is in progress to determine if antivirals ameliorate its development. What is the evidence that HSV-1 is involved in AD?
[Read more…] about Herpes simplex virus and Alzheimer’s disease
The TWiV hosts review persistence of Ebola virus after the end of the Liberian outbreak, and the potential role of two herpesviruses in the pathogenesis of Alzheimer’s disease.
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Download TWiV 505 (74 MB .mp3, 122 min)
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Show notes at microbe.tv/twiv
Risk factors for the chronic neurodegenerative condition known as Alzheimer’s disease (AD) include many cellular genes and pathogenic microbes. Nucleic acids of two ubiquitous human herpesviruses, HHV-6A and HHV-7, have been found at higher levels in AD brains compared with healthy controls, and appear to regulate genes implicated in risk of developing the disease.