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About viruses and viral disease

aedes aegypti

A risky vaccine

9 May 2019 by Gertrud U. Rey

Dengvaxiaby Gertrud U. Rey

Dengue fever, caused by dengue virus (DENV), is of substantial public health significance in the tropics, where the virus is spread by Aedes mosquitoes. Last week the FDA announced its approval of a first vaccine for the prevention of dengue disease in endemic areas.

[Read more…] about A risky vaccine

Filed Under: Basic virology, Commentary, Gertrud Rey, Information Tagged With: aedes aegypti, antibody dependent enhancement, dengue hemorrhagic fever, dengue virus, Dengvaxia, vaccine, viral, virology, virus, viruses

TWiV 506: A Cafeteria full of jelly rolls

12 August 2018 by Vincent Racaniello

The TWiVniks explain how the three-dimensional structure of the giant Cafeteria roenbergensis virus suggests a new mode of assembly, and the apparent elimination of dengue fever in an Australian city by release of mosquitoes harboring Wolbachia.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: aedes aegypti, bacteriovore, Cafeteria roenbergensis virus, cryoEM, dengue fever, giant virus, spiral assembly, vaccines, viral, virology, virus, virus structure, viruses, wolbachia

TWiV 498: Salivating at ASM Microbe

17 June 2018 by Vincent Racaniello

Vincent, Kathy and Rich travel to ASM Microbe 2018 in Atlanta where they speak with Stacy Horner and Ken Stapleford about their careers and their research.

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Show notes at microbe.tv/twiv

Filed Under: This Week in Virology Tagged With: aedes aegypti, Aedes albopictus, alphavirus, ASM Microbe 2018, Chikungunya virus, epitranscriptome, evolution, m6 adenosine, m6A, quasispecies, RNA, RNA modification, viral, virology, virus, viruses

TWiV 388: What could possibly go wrong?

8 May 2016 by Vincent Racaniello

TWiVPreprint servers, the structure of an antibody bound to Zika virus, blocking Zika virus replication in mosquitoes with Wolbachia, and killing carp in Australia with a herpesvirus are topics of episode #388 of the science show This Week in Virology, hosted by Vincent, Dickson, Alan, and Kathy.

You can find TWiV #388 at microbe.tv/twiv, or listen below.

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Download TWiV 388 (73 MB .mp3, 101 min)
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Filed Under: This Week in Virology Tagged With: aedes aegypti, antibody, biological control, biorXiv, carp, Cyprinid herpesvirus 3, Koi, koi herpesvirus, mosquito, myxomavirus, preprint server, rabbits, viral, virology, virus, viruses, wolbachia, zika virus, Zika virus vaccine

TWiV 115: Color me infected

9 January 2011 by Vincent Racaniello

brainbow pseudorabies virusHosts: Vincent Racaniello, Alan Dove, Rich Condit, and Marc Pelletier

On episode #115 of the podcast This Week in Virology, Vincent, Alan, Rich and Marc discuss the finding that a limited number of incoming herpesviral genomes can replicate and express in a cell, and controlling viral replication in Aedes aegypti with a Wolbachia symbiont.

[powerpress url=”http://traffic.libsyn.com/twiv/TWiV115.mp3″]

Click the arrow above to play, or right-click to download TWiV #115 (84 MB .mp3, 117 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

  • Replication and expression of limited numbers of incoming viral genomes
  • The brainbow cassette
  • Release of Wolbachia infected mosquitoes in Australia (story one, two)
  • Journal articles on Wolbachia infection of mosquitoes (Cell, PloS Pathogens)
  • Wolbachia discussion on TWiV 61
  • TWiV on Facebook
  • Letters read on TWiV 115

Weekly Science Picks

Marc – Homebrew bioreactor (photo, movie) – culture bottle and drive, oil-free vacuum pumps
Rich –
Logitech Harmony Universal Remote
Alan – H.M.S. Challenger Reports
Vincent – Sequence of the strawberry genome and blog post by lead author

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: aedes aegypti, brainbow, Chikungunya, Dengue, herpesvirus, malaria, mosquito, plaque, pseudorabies virus, replication, viral, virology, virus, wolbachia

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

With David Tuller and
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