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adeno-associated virus

TWiV 448: Mavis the Structure Maven

2 July 2017 by Vincent Racaniello

From ASV 2017 in Madison, Wisconsin, the complete TWiV team speaks with Mavis Agbandje-McKenna about her career and her work solving virus structures by x-ray crystallography and cryo-electron microscopy.

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Show notes at microbe.tv/twiv

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Filed Under: This Week in Virology Tagged With: aav, adeno-associated virus, cryo-electron microscopy, cryoEM, Mavis Agbandje-McKenna, viral, virology, virus, virus structure, virus vector, X-ray crystallography

TWiV 350: Viral gene therapy with Katherine High

16 August 2015 by Vincent Racaniello

On episode #350 of the science show This Week in Virology, Vincent speaks with Katherine High about her career and her work on using viral gene therapy to treat inherited disorders.

This episode is drawn from one of twenty-six video interviews with leading scientists who have made significant contributions to the field of virology, part of the new edition of the textbook Principles of Virology.

You can find TWiV #350 at www.microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: aav, adeno-associated virus, blindness, factor IX, gene therapy, hemophilia, Katherine High, Leber's congenital amaurosis, monogenetic, vector, viral, virology, virus

TWiV 326: Giving HIV a flat tyr

1 March 2015 by Vincent Racaniello

On episode #326 of the science show This Week in Virology, the sternutating TWiVers discuss preventing infection of cells and animals by a soluble CD4-CCR5 molecule that binds to HIV-1 virus particles.

You can find TWiV #326 at www.microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: aav, adeno-associated virus, CD4, eCD4-Ig, gene therapy, HIV, human immunodeficiency virus, immunoadhesin, immunoglobulin, sCD4-Ig, SHIV, simian immunodeficiency virus, siv, viral, virology, virus

TWiV 236: Flu gets the VIP treatment

9 June 2013 by Vincent Racaniello

On epside #236 of the science show This Week in Virology, Vincent, Alan and Kathy review novel approaches to preventing influenza virus infection.

You can find TWiV #236 at www.microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: aav, adeno-associated virus, broadly neutralizing antibody, codon pair bias, ferret, HA, hemagglutinin, influenza, mouse, NA, neuraminidase, vaccine, vector, vectored immunoprophylaxis, viral, virology, virus

TWiV 212: Apocalypse TWiV 122112 212

23 December 2012 by Vincent Racaniello

On episode #212 of the science show This Week in Virology, the TWiVerers answer listener email about genetically modified chickens, a hendra vaccine for horses, online education, curing color blindness, Roosevelt and polio, Th cells, and much more.

You can find TWiV #212 at www.microbe.tv/twiv.

Filed Under: This Week in Virology Tagged With: adeno-associated virus, coronavirus, email, GM food, Guillain-Barré, H3N2, HeLa, Hendra, herpes, influenza, listener, MOOC, norovirus, phage, SARS, viral, viral vector, virology, virus

TWiV 168: Super CalTech prophylaxis and ferret runny noses

29 January 2012 by Vincent Racaniello

adeno-associated virusHosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Welkin Johnson

Welkin joins the TWiV team for a discussion of HIV prophlaxis using vectored antibodies, and the influenza H5N1 virus studies in ferrets that were not redacted.

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Click the arrow above to play, or right-click to download TWiV 168 (59 MB .mp3, 98 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

  • Vectored HIV immunoprophylaxis (Nature)
  • Vectored immunoprophylaxis – the Movie (YouTube)
  • Adeno-associated virus (Wikipedia)
  • In vitro evolution of H5N1 towards human receptor specificity (Virology)
  • Endogenous viral genes non-essential in chicken (Nature)
  • Rates of HIV transmission per coital act (J Inf Dis)
  • TWiV on Facebook
  • Letters read on TWiV 168

Weekly Science Picks

Welkin – Virtual PI (Nature)
Dickson – Drain the Ocean
Rich – Nova: To the Moon
Alan - Robert Falcon Scott on Twitter and the Terra Nova expedition
Vincent – Hello, Mr. Chips (I, Cringely)

Listener Pick of the Week

Charlotte – And the Band Played On

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: aav, adeno-associated virus, AIDS, antibody, evolution, ferret, H5N1, immunoprophylaxis, influenza, receptor, vector, viral, virology, virus

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

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