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About viruses and viral disease
Amy joins the TWiV team to review evidence that enterovirus D68 is an etiologic agent of childhood paralysis, and her finding that the ability of the virus to infect cells of the nervous system is not a recently acquired property.
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Download TWiV 572 (73 MB .mp3, 121 min)
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Show notes at microbe.tv/twiv
with Amy Rosenfeld
Enterovirus D68 (EV-D68) was first isolated from children with respiratory disease in 1962. No outbreaks of infection were detected until the late summer and early fall of 2014, and then in 2016 and 2018. During these epidemics of respiratory disease, some children developed polio-like paralysis. We have recently published a paper showing that isolates of EV-D68 from 1962 through 2014 are capable of infecting cells of the nervous system, disproving the hypothesis that neurotropism of the virus is a recently acquired phenotype.
[Read more…] about Neurotropism of enterovirus D68 is not a recently acquired property
In the second episode from the Karolinska Institute in Stockholm, Vincent speaks with Jan Albert, Petter Brodin, and Anna Smed-Sörensen about their work on enterovirus D68, systems immunology, and human pulmonary viral infection and inflammation.
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Download TWiV 568 (58 MB .mp3, 95 min)
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Show notes at microbe.tv/twiv
On episode #331 of the science show This Week in Virology, the TWiVÂ team discusses the possible association of the respiratory pathogen enterovirus D68 with neurological disease.
You can find TWiV #331 at www.microbe.tv/twiv.