TWiV 975: Crossing the Ts with Daniela Weiskopf

Daniela joins TWiV to discuss her career and her research on T cells, their role in infection with SARS-CoV-2, T cell epitopes and why a variant that evades T cell immunity is not likely to emerge. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Guest: Daniela Weiskopf Click arrow to playDownload TWiV 975 (58 MB .mp3, 98 …

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When Two Different Viruses Have Offspring

by Gertrud U. Rey Have you ever wondered what would happen if you were infected with two different viruses at the same time? A recent study aimed at addressing this question has produced some astounding new findings. The authors of the study wanted to observe the interactions between respiratory syncytial virus (RSV) and influenza A …

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TWiV 966: 1918 influenza with Jeffery Taubenberger

Vincent travels to the NIH campus to speak with Jeffery Taubenberger about his career, the 1918 influenza pandemic, deciphering the genome sequence of the virus from tissues of disease victims and using it to rescue infectious virus.

“Paxlovid Rebound” Is Just COVID Rebound

by Gertrud U. Rey The antiviral drug Paxlovid is highly effective at inhibiting SARS-CoV-2 replication and reducing symptoms associated with COVID-19. Nevertheless, there have recently been numerous reports of recurrence of positive tests and symptoms after completing treatment with Paxlovid, leading some to infer that the drug triggers the recurrence. Is this inference actually correct, …

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TWiV 954: Speculating sarbecovirus spillovers with Michael Letko

Michael Letko joins TWiV to discuss his research on understanding cell receptors required for sarbecovirus entry, including an ACE2-dependent isolate from Russian bats that is resistant to vaccine-induced antibodies.

TWiV 953: Clinical update with Dr. Daniel Griffin

In his weekly clinical update Dr. Griffin discusses high demand for Amoxicillin causing shortages amid child RSV surge, epidemiologic and clinical features of children and adolescents aged <18 years with monkeypox, low risk of SARS-Cov-2 transmission by fomites, nucleocapsid antigenemia is a marker of acute SARS-CoV-2 infection, impact of community masking on COVID-19,  protection against Omicron from vaccination and …

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Trial By Error: Betsy Ladyzhets on Problems with NIH’s RECOVER Initiative

By David Tuller, DrPH Science journalist Betsy Ladyzhets, co-founder and co-editor of The Sick Times, has been covering the problemls with RECOVER, the $1.15 billion Long Covid initiative from the US National Institutes of Health. Ladyzhets recently wrote a new article about RECOVER, published in The Sick Times as well as STAT, based on documents …

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Trial By Error: Professor Esther Crawley, Bristol University’s Methodologically and Ethically Challenged Pediatrician, Has Retired From Medicine

By David Tuller, DrPH Professor Esther Crawley, Bristol University’s methodologically and ethically challenged pediatrician and long-time grant magnet, gave up her right to practice medicine last September, according to her current entry at the UK’s General Medical Council, which oversees the registration of physicians. The entry does not offer an explanation for why Professor Crawley …

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Trial By Error: The Michael Sharpe Crowdfunding Effect

By David Tuller, DrPH *This is a crowdfunding month for Trial By Error. Donations (tax-deductible to US tax-payers) go to the University of Calinfornia, Berkeley, to support the project. The link to the crowdfunding campaign is here: https://crowdfund.berkeley.edu/project/42302 In the past, Professor Michael Sharpe, one of the lead PACE investigators, has intervened in my Berkeley crowdfunding …

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Trial By Error: BBC Takes on Lightning Process and Highlights Perspectives of the So-Called “Anti-Recovery Activists”

By David Tuller, DrPH *This is a crowdfunding month for Trial By Error. Donations (tax-deductible to US tax-payers) go to the University of Calinfornia, Berkeley, to support the project. The link to the crowdfunding campaign is here: https://crowdfund.berkeley.edu/project/42302 UPDATE: At the end of this post, I mentioned the patient in the BBC report who said she …

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Trial By Error: Anil van der Zee’s New Video on Living with Severe ME

By David Tuller, DrPH *This is a crowdfunding month for Trial By Error. Donations (tax-deductible to US tax-payers) go to the University of Calinfornia, Berkeley, to support the project. The link to the crowdfunding campaign is here: https://crowdfund.berkeley.edu/project/42302 ********** Anil van der Zee and I first connected in 2016, when he invited me to Amsterdam to …

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Trial By Error: Time’s Health100 List Includes Leaders in Long Covid and ME/CFS

By David Tuller, DrPH *This is a crowdfunding month for Trial By Error. Donations (tax-deductible to US tax-payers) go to the University of Calinfornia, Berkeley, to support the project. The link to the crowdfunding campaign is here: https://crowdfund.berkeley.edu/project/42302 Last week, Time magazine unveiled a list called the TIME100 Health—a selection of “leaders from across industries—scientists, doctors, …

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