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TWiV 937: Pediatric hepatitis with Emma Thomson

18 September 2022 by Vincent Racaniello 1 Comment

From the European Society for Clinical Virology 2022 Conference in Manchester UK, Vincent speaks with Emma Thomson about the recent outbreak of pediatric hepatitis of unknown etiology and the finding that it is linked to infection by adenovirus-associated virus 2.

Hosts: Vincent Racaniello

Guest: Emma Thomson

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Links for this episode

Thomson laboratory 00:42
Emma on TWiV 188 and TWiV 341 00:52
AAV2-associated pediatric hepatitis (bioRxiv) 3:18
Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 936: Clinical update with Dr. Daniel Griffin

17 September 2022 by Vincent Racaniello Leave a Comment

In his weekly clinical update Dr. Griffin discusses detection of a highly divergent type 3 vaccine-derived poliovirus in a child with a severe primary immunodeficiency disorder, severe respiratory illnesses associated with rhinoviruses and/or enteroviruses including EV-D68, effects of vaccination and previous infection on Omicron infections in children, COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years or older in 13 US states, effectiveness of COVID-19 vaccines over time prior to Omicron emergence in Ontario, Canada, nasal IgA wanes 9 months after hospitalization with COVID-19 and is not induced by subsequent vaccination, resistance of SARS-CoV-2 Omicron subvariant BA.4.6 to antibody neutralization, persistent circulating SARS-CoV-2 spike associated with post-acute COVID-19 sequelae, and impact of COVID-19 vaccination on the risk of developing long-covid and on existing long-covid symptoms.

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Download TWiV 936 (31 MB .mp3, 52 min)
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Show notes at microbe.tv/twiv

Trial By Error: Psychological Medicine Rejects Letter About Chalder’s Bogus Review of CBT/GET Studies

16 September 2022 by David Tuller 3 Comments

By David Tuller, DrPH

Professor Trudie Chalder recently published a systematic review of CBT and GET studies for “chronic fatigue syndrome” in the journal Psychological Medicine, which seems to publish anything from the CBT/GET ideological brigades, no matter how poorly conducted or reported. Not surprisingly, given its provenance, the review was a piece of crap, as I noted in a recent post. I wrote a letter to the journal about it. Not surprisingly, they rejected it. Also not surprisingly, I responded. Below is our exchange.

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Trial By Error: Journalist Ryan Prior Discusses His Upcoming Book on Long Covid, The Long Haul

13 September 2022 by David Tuller 2 Comments

By David Tuller, DrPH

CNN journalist Ryan Prior is the author of an upcoming book on long Covid called The Long Haul: Solving the Puzzle of the Pandemic’s Long Haulers and How They Are Changing Healthcare Forever. Ryan, who is 32, has struggled with ME/CFS for half of his life—he first got sick in October, 2006, just before his 17^th birthday, and was diagnosed the following year. His documentary about the illness, Forgotten Plague, was released in 2015.

Trial By Error: My Exchange of Letters With Bristol About Professor Crawley’s Uncorrected Ethics Statements

12 September 2022 by David Tuller 3 Comments

By David Tuller, DrPH

I recently reported that seven papers from Professor Esther Crawley, Bristol University’s methodologically and ethically challenged pediatrician and grant magnet, do not appear to have been corrected, as requested almost three years ago by a report of an investigation into her work. The investigation was commissioned by Bristol along with the UK’s Health Research Authority, which overseas ethics concerns.

Trial By Error: My Letter to Psych Medicine About Professor Chalder’s Flawed Systematic Review

9 September 2022 by David Tuller 7 Comments

By David Tuller, DrPH

Earlier this week, I wrote about the bogus systematic review of treatment trials for “chronic fatigue syndrome” published this month by Professor Trudie Chalder in Psychological Medicine. In many respects, as I noted, this journal functions a an in-house marketing or public relations organ for members of the CBT/GET ideological brigades, of which Professor Chalder is a charter member. (Professors Michael Sharpe and Simon Wessely are on the Psychological Medicine editorial board. Enough said.)

In addition to formally submitting the article through the journal’s online portal, I also posted it on a pre-print server and sent it directly to the two co-editors of the journal. Here it is.