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About viruses and viral disease

Vincent Racaniello

TWiV 902: Autoantibodies drive severe COVID-19

22 May 2022 Leave a Comment

TWiV reviews recent cases of monkeypox, presence of SARS-CoV-2 RNA but not infectious virus in feces, and the association of autoantibodies to interferons with severe COVID-19.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker

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Show notes at microbe.tv/twiv

TWiV 901: COVID-19 clinical update #115 with Dr. Daniel Griffin

21 May 2022 Leave a Comment

In COVID-19 clinical update #115, Dr. Griffin reviews cross-variant immunity without vaccination, EUA for boosters in 5-11 year olds, B.1.1.529 attack rate, scent dogs, Omicron and pets, Paxlovid, Veklury, Fluvoxamine, antigen positivity after isolation, inflammasome activation and severe disease, and GI persistence and fecal shedding.

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Show notes at microbe.tv/twiv

TWiV 900: Burning down the mouse

15 May 2022 Leave a Comment

TWiV celebrates 900 episodes, Vincent gives the Richard R. Ernst lecture, and we discuss why inflammasome activation in infected macrophages drives severe COVID-19.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Show notes at microbe.tv/twiv

TWiV 896: Memory B cells, the way we were

1 May 2022 2 Comments

TWiV explains a study of how climate change is predicted to increase cross-species viral transmission risk, and increased memory B cell potency and breadth after a SARS-CoV-2 mRNA vaccine boost.

Hosts: Vincent Racaniello, Dickson Despommier, and Amy Rosenfeld

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Show notes at microbe.tv/twiv

TWiV 895: COVID-19 clinical update #112 with Dr. Daniel Griffin

30 April 2022 1 Comment

In COVID-19 clinical update #112, Dr. Griffin reviews seroprevalence of infection-induced antibodies, Moderna filing for vaccine authorization in young children, public health impact of vaccines in US, FDA approval of first treatment for young children, phase 2 data for Sabizabulin, and post infection inflammation.

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Show notes at microbe.tv/twiv

TWiV 894: Dinner with the TMPRSS family

28 April 2022 Leave a Comment

TWiV explains what is known about cases of acute, severe hepatitis of unknown origin in children, and discovery of an inhibitor of TMPRSS2 protease that blocks SARS-CoV-2 infection.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

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Show notes at microbe.tv/twiv

TWiV 891: LLOV in the time of Ebola

21 April 2022

Elke, Adam, and Gabor join TWiV to discuss their work on Lloviu virus, a filovirus, including recovery of infectious virus from a DNA copy of the genome and from Schreiber’s bats in Hungary.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

Guests: Elke Muhlberger, Adam Hume, and Gabor Kemenesi

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Show notes at microbe.tv/twiv

TWiV 890: Looking into a booster crystal ball

18 April 2022

This episode of TWiV is focused on COVID-19 vaccines and antibodies: who should get boosters, whether a variant matched mRNA vaccine is superior to a historical vaccine, and how the interval between vaccination and infection influences the quality of the antibody response.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

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Show notes at microbe.tv/twiv

TWiV 889: COVID-19 clinical update #110 with Dr. Daniel Griffin

16 April 2022

In COVID-19 clinical update #110, Dr. Griffin covers hospital admissions during variant outbreaks, viral load in vaccinated and unvaccinated individuals, predictive capacity of symptoms in children, comparison of antigen tests, incidence of myocarditis after vaccination, steroids during replication phase, Paxlovid efficacy and safety, fluvoxamine, sabizabutin, colchicine, and prevalence of infection in Africa.

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Show notes at microbe.tv/twiv

TWiV 888: Molnupiravir with Richard Plemper

14 April 2022

Richard joins TWiV to discuss the SARS-CoV-2 antiviral drug Molnupiravir , including how it was discovered, its mechanism of action, whether it is a mutagen for cells, and the future of drugs for treatment of COVID-19.

Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker

Guest: Richard Plemper

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Show notes at microbe.tv/twiv

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by Vincent Racaniello

Earth’s virology Professor
Questions? virology@virology.ws

With David Tuller and
Gertrud U. Rey

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Contents

Table of Contents
ME/CFS
Inside a BSL-4
The Wall of Polio
Microbe Art
Interviews With Virologists

Earth’s Virology Course

Virology Live
Columbia U
Virologia en Español
Virology 101
Influenza 101

Podcasts

This Week in Virology
This Week in Microbiology
This Week in Parasitism
This Week in Evolution
Immune
This Week in Neuroscience
All at MicrobeTV

Useful Resources

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HealthMap
Polio eradication
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Small Things Considered
ViralZone
Virus Particle Explorer
The Living River
Parasites Without Borders

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