TWiV 596: COVID-19 – an ounce of prevention

TWiV covers trials of hydroxychloroquine and convalescent plasma therapy for COVID-19, and answers listener questions on blood tests for antibodies, cross-protection among coronaviruses, acquiring infection from food or the gas pump, face masks containing copper, and much more.

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  • Walter Morykon 14 April 2020, 8:38 am

    My bad
    Also quercetin exhibits immunomodulatory effects by increasing cytokine production ….
    8. 27 Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw. 2001; 12 290-296

    Should read
    In addition quercetin can inhibit viral replication at different stages of the viral lifecycle (8,9)
    And has immunomodulatory effects that it exerts through a number of different mechanisms (10)

    8. Liu, Z., Zhao, J., Li, W. et al. Computational screen and experimental validation of anti-influenza effects of quercetin and chlorogenic acid from traditional Chinese medicine. Sci Rep 6, 19095 (2016).

    9. Wu, W.; Li, R.; Li, X.; He, J.; Jiang, S.; Liu, S.; Yang, J. Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry. Viruses 2016, 8, 6.

    10. Li, Y.; Yao, J.; Han, C.; Yang, J.; Chaudhry, M.T.; Wang, S.; Liu, H.; Yin, Y. Quercetin, Inflammation and Immunity. Nutrients 2016, 8, 167.

    Again thank you all for the great work you are doing.
    Truly a pleasure to listen to your podcasts, and the blog posts.