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TWiV 160: Moore tumor viruses

4 December 2011 by Vincent Racaniello

merkel carcinomaHosts: Vincent Racaniello, Rich Condit, Alan Dove, Dickson Despommier, and Patrick Moore

The TWiV team speaks with Patrick Moore about his discovery, with Yuan Chang, of two human tumor viruses, Kaposi’s sarcoma herpesvirus and Merkel cell polyomavirus.

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Click the arrow above to play, or right-click to download TWiV 160 (66 MB .mp3, 109 minutes).

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Links for this episode:

  • Chang-Moore laboratory at University of Pittsburgh
  • Representational difference analysis (Science)
  • KSHV: Forgotten but not gone (Blood)
  • Why do viruses cause cancer? (Nat Rev Cancer)
  • Merkel cell carcinoma review (Ann Rev)
  • Clonal integration of a polyomavirus in Merkel carcinoma (Science)
  • T antigen mutations in Merkel polyomavirus (PNAS)
  • Merkel polyomavirus small t is an oncoprotein (J Clin Inves)
  • Suggest a topic for the 2012 ASM General Meeting
  • TWiV on Facebook
  • Letters read on TWiV 160

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Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Filed Under: This Week in Virology Tagged With: cancer, kaposi, kshv, merkel, polyomavirus, sarcoma, tumor virus, viral, virology, virus

Reader Interactions

Comments

  1. Nick says

    6 December 2011 at 9:19 am

    Great episode! It is astounding that infections are causative to so many cases of cancer while this fact is neither represented in the media, nor in funded research. If you look at a list not limited to cancer the association between infection and chronic disease gets even stronger.

    http://en.wikipedia.org/wiki/List_of_human_diseases_associated_with_infectious_pathogens

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