I'm not sure that anyone has tried very hard to develop a plaque assay. The virus is cytopathic, yet the relevant cells for infection are lymphocytes, which don't adhere to plastic dishes. Therefore developing a plaque assay would not be straightforward.
gsgssays
http://latimesblogs.latimes.com/booster_shots/2… The researchers extracted white blood cells from all the subjects and exposed them to HIV in a culture dish. They reported in the journal BMC Immunology that HIV replication was slowed by about 80% in the cells from those who had received smallpox vaccination.
Why doesn't HIV form plaques in any types of cells?
I'm not sure that anyone has tried very hard to develop a plaque
assay. The virus is cytopathic, yet the relevant cells for infection
are lymphocytes, which don't adhere to plastic dishes. Therefore
developing a plaque assay would not be straightforward.
http://latimesblogs.latimes.com/booster_shots/2…
The researchers extracted white blood cells from all the subjects and exposed them to HIV in a culture dish. They reported in the journal BMC Immunology that HIV replication was slowed by about 80% in the cells from those who had received smallpox vaccination.
nice theme. but it takes a while to load