Hosts: Vincent Racaniello and Rich Condit
On episode #81 of the podcast This Week in Virology, Vincent and Rich answer listener questions on viruses and gluten allergy, RNA silencing, influenza virus, herpes simplex virus, HIV/AIDS, chronic fatigue syndrome, manicure salons, and the koala tea of Marseilles.
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Click the arrow above to play, or right-click to download TWiV #81 (68 MB .mp3, 94 minutes)
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Links for this episode:
- Virus infections and gluten intolerance on TWiS (thanks Jesper!)
- Viral small RNAs in PLoS Pathogens (thanks Jason!)
- Canadian Summit Awards (thanks Jim!)
- Experimenting with phage at home (thanks Richard!)
- CRISPR discovered by a dairy company (thanks Joel!)
- Expedition to New Guinea to sample bird viruses – movie and blog entry (thanks Henrik!)
- Preventing herpes with arginine and lysine – pdf (thanks Anthony!)
- Chronic fatigue donors face rejection (thanks James!)
- The Koala tea of Marseilles is not strained (thanks Stephen!)
- The other Larson virus cartoon (jpg)
- Letters read on TWiV 81
Weekly Science Picks
Rich Google Chrome browser ‘speed test‘ (and how it was made)
Vincent Inside the Outbreaks by Mark Pendergrast
Send your virology questions and comments (email or mp3 file) to email@example.com or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.
K. Benson says
On May 10, 2010 the CFS scientific advisory committee to the Department of Health and Human Services voted unanimously to recommend that patients diagnosed with CFS and patients with a previous diagnosis of CFS refrain from donating blood. Members of the committee include biomedical and behavioral researchers, clinicians, and educators who are CFS experts.
A number of issues were raised: cyclical nature of infectious disease; association between CFS and several cancer causing viruses in addition to XMRV; low blood volume of CFS patients and the need to err on the side of caution.
The vote followed a presentation by Dr. Jerry Holmberg of the HHS Blood Safety Committee. All agreed that further data and standardization is warranted.
Although organ donation was not addressed, the need for information on viral reservoirs may also become an issue.
A wise decision. Do we know what fraction of the US blood supply has
been provided by CFS patients?
K. Benson says
The short answer is no.
This is partly because most donation centers do not ask about CFS or a history of CFS they only ask, â€œAre you feeling well todayâ€ which committee members pointed out is vague and subjective.
Another reason may be that many biomedical and behavioral researchers believe CFS is an umbrella diagnosis drawing in severely ill patients with post-exertional malaise upon relatively little exertion, not relieved by rest and lasting longer than 24-hours and plain old tired people alike.
Because only the restrictive 2003 Canadian Consensus definition, used by Lombardi et al, requires severity as well as duration as part of a differential diagnosis, epidemiological studies donâ€™t even agree on how many CFS patients there may actually be much less who may be donating blood while in remission.
Dr. Holmberg doesn't believe the numbers are significant.
Gluten Intolerance says
I donâ€™t want to be a virus. Iâ€™m already fine with my whole world. LOL. There are now lots of virus around the world causing thousands of people died. Thanks for posting the different links of episode.