Hosts: Vincent Racaniello and Dick Despommier
On episode #47 of the podcast “This Week in Virology”, Vincent and Dick discuss influenza virus-like particle vaccines produced in insect and plant cells, rapid sharing of influenza research, and answer listener questions about cytomegalovirus, viral evolution and symbiosis and much more.
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Links for this episode:
A Farm on Every Floor
Influenza virus-like particles in insect and plant cells
PLoS Currents: Influenza
Transmission of 2009 H1N1 influenza virus to turkeys [Thanks Debbie!]
Baxter produces Vero cell H1N1 vaccine [Thanks Peter!]
Boundaries of Darwinism podcast [Thanks David!]
Phages in human intestine: papers one, two, three [Thanks Terry!]
Post-exposure varicella vaccine [Thanks Patricia!]
Open science movement here, here, here, and here [Thanks Jim!]
Graduate programs in virology [Thanks Greggory and Blake!]
Post-exposure Marburg and Ebola vaccines [Thanks John!]
Vaccinia infection in the laboratory [Thanks Russ!]
Animations of bacteriophage T4 life cycle [Thanks Jim!]
Weekly Science Picks
Vincent Bionumbers
Dick Ocean: An Illustrated Atlas by Sylvia A. Earle, Linda K. Glover
Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv or leave voicemail at Skype: twivpodcast
Plant derived virus particles are definitely practical. There are a number of plant viruses that are excellent for that purpose. Tobacco is a nice plant to use because of TMV (tobacco mosaic virus), but there are others. There are good methods for purification such as Watanabe 1952 or Gooding 1967 http://www.ncbi.nlm.nih.gov/pubmed/6075009
Early vaccine studies have been done. (Ex: http://www.nature.com/nbt/journal/v13/n1/abs/nb… )
Try talking to Bryce Falk at UCD. He's very knowledgable about TMV and other viruses for protein expression. bwfalk@ucdavis.edu
Plant derived virus particles are definitely practical. There are a number of plant viruses that are excellent for that purpose. Tobacco is a nice plant to use because of TMV (tobacco mosaic virus), but there are others. There are good methods for purification such as Watanabe 1952 or Gooding 1967 http://www.ncbi.nlm.nih.gov/pubmed/6075009
Early vaccine studies have been done. (Ex: http://www.nature.com/nbt/journal/v13/n1/abs/nb… )
Try talking to Bryce Falk at UCD. He's very knowledgable about TMV and other viruses for protein expression. bwfalk@ucdavis.edu