SARS

COVID-19 and SARS-CoV-2 on TWiV

I’ve been delinquent in posting recent episodes of This Week in Virology here. They are all focused on SARS-CoV-2 and the disease it causes, COVID-19. Here is a list: TWiV Special: Coronavirus update with Mark Denison, MD Pediatric infectious disease physician and coronavirologist Mark Denison joins Vincent for a discussion of COVID-19 and SARS-CoV-2 with …

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A lesson from SARS-CoV for 2019-nCoV

As with all previous outbreaks of new virus infections, we are being warned of impending doom concerning the new coronavirus, 2019-nCoV that is now spreading globally. China€™s National Health Commission Vice Minister Li Bin recently warned that ‘there is the possibility of viral mutation€™. Perhaps Mr. Li is unaware that viral genomes sustain mutations during …

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TWiV 501: Outbreak

Vincent visits the Smithsonian Institution and speaks with Sabrina Sholts, Jon Epstein, and Ed Niles about the exhibit Outbreak: Epidemics in a Connected World. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span>&lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&gt;&lt;/span&gt;&amp;lt;span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”&amp;gt;&amp;lt;/span&amp;gt;&amp;amp;lt;span …

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Genome recombination across viral families

 A novel coronavirus isolated from bats in China is unusual because the genome contains a gene from a virus in a completely different family, the Reoviridae (link to paper). The finding suggests that recombination occurred between a (+) strand RNA virus and a virus with a segmented, double-stranded RNA genome. The unusual recombinant virus was identified …

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