TWiV 387: Quaxxed

TWiVOn episode #387 of the science show This Week in Virology, Nina Martin joins the TWiV team to talk about the movie Vaxxed, her bout with dengue fever, and the latest research on Zika virus.

You can find TWiV #387 at microbe.tv/twiv, or listen below.

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TWiV 322: Postcards from the edge of the membrane

On episode #322 of the science show This Week in Virology, the TWiVodes answer listener email about hantaviruses, antivirals, H1N1 vaccine and narcolepsy, credibility of peer review, Bourbon virus, influenza vaccine, careers in virology, and much more.

You can find TWiV #322 at www.microbe.tv/twiv.

TWiV 213: Not bad for a hobby

On the final episode of the year of the science show This Week in Virology, the TWiV team reviews twelve cool virology stories from 2012.

You can find TWiV #213 at www.microbe.tv/twiv.

Mumps in college

Morbidity and Mortality Weekly Report summarizes a mumps outbreak that occurred in 2011 on a university campus in California:

On September 29, 2011, the California Department of Public Health (CDPH) confirmed by polymerase chain reaction (PCR) three cases of mumps among students recently evaluated at their university’s student health services with symptoms suggestive of mumps. An investigation by CDPH, student health services, and the local health department identified 29 mumps cases. The presumed source patient was an unvaccinated student with a history of recent travel to Western Europe, where mumps is circulating. The student had mumps symptoms >28 days before the onset of symptoms among the patients confirmed on September 29. Recognizing that at least two generations of transmission had occurred before public health authorities were alerted, measles, mumps, and rubella (MMR) vaccine was provided as a control measure. This outbreak demonstrates the potential value of requiring MMR vaccination (including documentation of immunization or other evidence of immunity) before college enrollment, heightened clinical awareness, and timely reporting of suspected mumps patients to public health authorities.

All 29 cases were epidemiologically linked to the university. One of the cases was the source patient’s roommate who had received two doses of MMR (measles, mumps, rubella) vaccine. Other outbreaks of mumps have occurred in populations in which many individuals had received 2 doses of MMR.

Data collected during previous mumps outbreaks on college campuses indicate that extended person-to-person contact, in combination with waning vaccine-induced immunity, might make colleges and universities high-risk settings for outbreaks, even when 2-dose MMR vaccination coverage is high

CDC suggests that all colleges and universities consider requiring documentation that students have received 2 doses of MMR vaccine before matriculation.

The mumps vaccine was licensed in the US in 1967, resulting in a significant decline in the number of cases. However outbreaks continue to occur, even in immunized populations, when the virus is introduced by overseas travelers. The vaccine is included in national health programs of only 62% of countries, and immunization rates have declined in many European countries, leading to outbreaks of measles and mumps.

TWiV 183: Bats out of hell

On episode #183 of the science show This Week in Virology, Connor Bamford joins the TWiV team to discuss bats as hosts for major mammalian paramyxoviruses.

You can find TWiV #183 at www.microbe.tv/twiv.

TWiV 172: Two can be as bad as one

On episode #172 of the podcast This Week in Virology, Vincent and Kathy discuss how a virus may cause disease distant from its replication site, then review a day in the life of a senior microbiology professor.

You can find TWiV #172 at www.microbe.tv/twiv.

TWiV 166: Breaking and entering

npc1 ebolaHosts: Vincent Racaniello, Dickson DespommierRich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan review cell proteins essential for entry of hepatitis C, Ebola, and measles viruses.

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Click the arrow above to play, or right-click to download TWiV 166 (59 MB .mp3,  98 minutes).

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Links for this episode:

Weekly Science Picks

Dickson – What are you swimming with?
Rich –
Twelve monkeys
AlanKindle Touch
Vincent – Microbe news (thanks to Dave Winer)

Listener Pick of the Week

EricThe Nature of Things with David Suzuki
LanceTrials and Errors (Wired)

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Virology lecture #20: Vaccines

Download: .wmv (314 MB) | .mp4 (82 MB)

Visit the virology W3310 home page for a complete list of course resources.

TWiV 48: Outbreaks near you

twiv_aa_2001Hosts: Vincent Racaniello, Dick DespommierAlan Dove, and Rich Condit

On episode 48 of the podcast “This Week in Virology”, Vincent, Dick, Alan and Rich revisit a vaccinia virus lab accident and viral vaccines produced in plants, then talk about an iPhone app to track infectious diseases, flying foxes, and an inhaled measles vaccine.

Click the arrow above to play, or right-click to download TWiV #48 (58 MB .mp3, 79 minutes)

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Links for this episode:
Laboratory acquired vaccinia infection
Medicago (investor presentation, pdf) and Fraunhofer produce vaccines in plants
iPhone app Outbreaks near me
No culling of flying foxes in Australia
Inhaled powdered measles virus vaccine
Herpesvirus latency confers symbiotic protection from bacterial infection (thanks Juliet!)
Porcine circovirus vaccine
Swine flu vaccine and Guillain-Barré (thanks Tom!)
The Great Flu and blog post (thanks Swiss compass and Allison!)
Building semiconductors with DNA (thanks Duncan!)
Email on viral classification (thanks Rodney and Eliot!)

Weekly Science Picks
Rich Stumbling on Happiness by Daniel Gilbert
Dick Eliot Porter at the Carter Museum and bookstore at Amazon
Alan Dr. Clarke’s H1N1 rap at the HHS sponsored YouTube contest
Vincent Coast to Coast Bio Podcast

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss to delicious and tagging them with to:twivpodcast.

TWiV 38: Measles

twiv-200Hosts: Vincent Racaniello and Glenn Rall

On episode #38 of the podcast “This Week in Virology”, Vincent and Glenn Rall chat about koi herpesvirus, H1N1 influenza vaccine produced in insect cells, attack by a rabid raccoon, and measles.

Click the arrow above to play, or right-click to download TWiV #38 (63 MB .mp3, 91 minutes)

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Links for this episode:
Virus suspected in carp die-off: koi herpesvirus
H1N1 influenza vaccine produced in insect cells with baculovirus vectors
Outbreak of measles in Wales
Production of influenza vaccines in cell cultures: MDCKVeroPER.C6EB66insect (thanks Peter!)

Weekly Science Picks
Glenn Riddled with Life by Marlene Zuk
Vincent All the Virology on the WWW

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv or leave voicemail at Skype: twivpodcast