germinal center

TWiV 685: Pandemicky

The TWiVers analyze efficacy of the AstraZeneca/Oxford adenovirus vectored vaccine, SARS-CoV-2 did not infect miners who became ill 8 years ago after cleaning bat guano from a cave in Yunnan Province, and induction of antigen-specific germinal center responses and production of neutralizing antibody by SARS-CoV-2 mRNA vaccine but not purified protein. Click arrow to playDownload TWiV …

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An explanation for the low quality antibodies produced during serious SARS-CoV-2 infection

Although we are less than a year into the SARS-CoV-2 pandemic, it appears that the antibodies induced by infection are often of poor quality, and B cell memory seems limited. An explanation for this outcome might be a consequence of the loss of germinal centers in COVID-19 patients. Examination of lymph nodes and spleen of …

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TWiV 161: Concerto in B

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Gabriel Victora Vincent, Rich, Alan and Gabriel review the production of antibodies by B cells, and how high affinity antibodies are selected in the germinal centers of lymph nodes. Please help us by taking our listener survey. [powerpress url=”http://traffic.libsyn.com/twiv/TWiV161.mp3″] Click the arrow above to play, or right-click to download …

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