.

Please help support our research to understand a new disease that is paralyzing children.

Visit our Columbia University Crowdfunding Site to make a tax-deductible contribution.
Your contribution will help us to understand the role of enterovirus D68 in childhood paralysis.

Paul Has Measles

pablotieneSusana López, Martha Yocupicio, Selene Zárate, virologists from Mexico, together with graphic illustrator Eva Lobatón, have teamed up to produce Paul Has Measles, a children’s book about viruses and vaccines.

Paul Has Measles is available in English (download link) or Spanish (download link).

Please share!

paulhasmeasles

By David Tuller, DrPH

The UK’s National Institute for Health and Care Excellence (NICE), which develops clinical guidelines for a range of medical conditions, is currently selecting a committee to develop a new guidance for the illness it refers to as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The new guidance will replace one written in 2007, when the organization was calling the illness CFS/ME. That 2007 guidance recommended graded exercise therapy (GET) and cognitive behavior therapy (CBT) as standard-of-care interventions and has been routinely cited as evidence that these treatments are effective.

[continue reading…]

TWiV 520: This old mouse

The TWiVidae review universal influenza vaccines that are in clinical trials, and discovery of an atypical parvovirus that causes chronic kidney disease in middle aged, immunocompromised laboratory mice.

Click arrow to play
Download TWiV 520 (70 MB .mp3, 116 min)
Subscribe (free): iTunesGoogle PodcastsRSSemail

Become a patron of TWiV!

Show notes at microbe.tv/twiv

Leaving Koch behind

parvovirusFor the past 40 years, certain laboratory mice in Australia and the US have been unexpectedly dying in middle age, but the cause has remained elusive. A novel member of the parvovirus family appears to be the culprit.

[continue reading…]

By David Tuller, DrPH

Here’s a video of back-to-back presentations from last month in Newry, Northern Ireland. On October 2, Brian Hughes, a professor of psychology at the National University of Ireland, Galway, and I both spoke at an event organized by Hope For ME & Fibro Northern Ireland. The title of the event: “The PACE Trial: ‘The Greatest Medical Scandal of This Century'”

Thanks to the organizers, volunteers, attendees and viewers!

https://www.facebook.com/Hope4MEFibro/videos/527084127758469/

By David Tuller, DrPH

I have written many posts about BMJ Open’s 2011 school absence study,
which reported that school absence records could be useful in identifying children with chronic fatigue syndrome. However, for reasons not yet adequately explained, the investigators exempted the study from ethical review on the grounds that it qualified as “service evaluation.” To support the claim, they cited a 2007 letter from the regional research ethics committee (REC), which was unrelated to the study in question.

[continue reading…]

The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer’s Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.

Click arrow to play
Download TWiV 519 (58 MB .mp3, 96 min)
Subscribe (free): iTunesGoogle PodcastsRSSemail

Become a patron of TWiV!

Show notes at microbe.tv/twiv

herpesvirusAlois Alzheimer was the first to propose that an infection might play a role in the disease named after him. Herpes simplex virus type 1 (HSV-1) has been most frequently linked to Alzheimer’s Disease (AD), and a clinical trial is in progress to determine if antivirals ameliorate its development. What is the evidence that HSV-1 is involved in AD?

[continue reading…]

By David Tuller, DrPH

Below is an exchange between members of the Australian ME/CFS community and Professor Michael Sharpe. The open letter from patients and advocates was prompted by a tweet this week from Professor Sharpe that many considered offensive. He has since deleted it. This post includes the initial tweet as well as the open letter and Professor Sharpe’s response.

**********

[continue reading…]

By David Tuller, DrPH

This morning I sent the following letter to Fiona Godlee, editor-in-chief of The BMJ and editorial director of BMJ. I cc-d Carol Monaghan MP, Darren Jones MP, and Nicky Morgan MP.

**********

[continue reading…]