A Pill to Prevent Gastroenteritis

by Gertrud U. Rey Norovirus is the most common food-borne virus and the leading cause of gastroenteritis globally. Despite an urgent need, there are currently no licensed vaccines to prevent norovirus-induced illness. Nevertheless, recent developments in this field have led to remarkable and promising new advances. A phase 1b clinical trial has revealed that a …

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H5N1 in U.S. Dairy Cattle: An Unprecedented Event in the History of Virology

by Fabrício Souza Campos  Fabrício Souza Campos is a virologist and professor at the Federal University of Rio Grande do Sul (UFRGS), Brazil. He coordinates the Graduate Program in Agricultural and Environmental Microbiology and leads research on virus surveillance in wildlife and domestic animals, with a focus on zoonotic threats and One Health. He has …

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A Vaccine Against Dementia

by Gertrud U. Rey The shingles vaccine is highly effective at preventing shingles, a painful rash caused by reactivation of varicella-zoster virus (VZV) – the herpes virus that also causes chickenpox. But what if this vaccine also prevented dementia? New data suggest that it just might. The authors of a recent multinational collaborative research study …

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Vitamin A, Cod Liver Oil, and Measles

by Gertrud U. Rey The number of measles cases is steadily increasing across the United States, especially in areas with low vaccination rates. Instead of recommending that children be vaccinated with the measles, mumps, and rubella (MMR) vaccine, US Health and Human Services Secretary Robert F. Kennedy Jr. continues to promote ideas that are rooted …

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West Nile Story

by Gertrud U. Rey On February 7, 2025, the world lost Dickson Despommier, a formidable parasitologist, gifted storyteller, and original co-host of the podcast This Week in Virology. Being a life-long learner, Dickson developed a keen interest in medical ecology, an interdisciplinary field that investigates how our ever-changing environment impacts human health. In his book …

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An Extremely Successful Vaccine Story

by Gertrud U. Rey One of the most noteworthy advances in biomedical science is the vaccine for human papillomavirus (HPV). It has significantly changed the diagnostic and prognostic landscape in the field of cervical cancer. Cervical cancer is the fourth most common cancer in women globally, and it is a particular problem in low-income countries …

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Trial By Error: An Essay on Living with Severe ME

By David Tuller, DrPH I’ve been totally out of commission for three weeks while recovering from bruised ribs sustained in a fall. I have devoted most of my time trying to find sitting and lying positions that did not cause excruciating pain. That part is over, and I’m slowly getting back to work and catching …

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Trial By Error: My Unexpected E-Mail Exchange with Alem Matthees

By David Tuller, DrPH In recent months, one of the most high-profile people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)—Australian Alem Matthees—has reported significant improvement in his condition. He is still bed-bound, and is still not speaking. This is not, by any means, “recovery.” Nonetheless, the change in Alem’s ability to read, consume information and communicate …

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Trial By Error: Journal Publishes Confusing Section on “Enduring Symptoms”

By David Tuller, DrPH As part of its December issue, Future Healthcare Journal, sponsored by the UK’s Royal College of Physicians, has published a special section called “Challenging Myths: Debunking Functional Disorders.” The special section title itself creates confusion. In what way are functional disorders being “debunked”? I assume the idea is to debunk the …

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Trial By Error: More on the Canadian Long COVID Trial with Plans to Lie to Participants Receiving an Exercise Intervention

By David Tuller, DrPH I recently posted a blog about the protocol for a Canadian Long COVID exercise trial in which the investigators proposed lying to the participants about the nature of both the study and the intervention being assessed.  While acknowledging that a significant number of people with Long COVID report experiencing post-exertional malaise …

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Trial By Error: In Protocol for Long COVID Exercise Trial, Investigators Advocate Lying to Participants

By David Tuller, DrPH Researchers are planning yet another trial of a rehabilitative exercise program for Long COVID—but, in this one, they propose to lie to all the participants about the nature of the study and the intervention being investigated. BMJ Open has recently published a paper called “Pursuing Reduction in Fatigue After COVID-19 via …

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Trial By Error: Some Things I’ve Read Recently: Anil van der Zee on Sex, “Mold Warrior” Johnson, and a Rant Against the Word “Journey”

By David Tuller, DrPH Anil van der Zee says “Fuck M.E.” One aspect of ME and ME/CFS that receives perhaps too little attention is the impact on someone’s sex life. Engaging in sexual activity takes a significant amount of energy—and is therefore likely to trigger post-exertional malaise for many with this illness. Especially for those …

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